Expertise

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  • Expertise in genomics and transcriptomics

    Expertise in genomics and transcriptomics

    Data Analysis - Analytics August 24, 2015 Check with publisher

    I lead the Integrative Genomics of Ageing Group (http://pcwww.liv.ac.uk/~aging/), and I have extensive experience in data analysis and integration of multidimensional data. Although my lab’s research integrates different strategies, its focal point i...

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  • ZP3 peptide

    ZP3 peptide

    Biology & Physiology Shirley (New York) February 22, 2019 Check with publisher

    The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this...

  • Wnt3 peptide

    Wnt3 peptide

    Biology & Physiology Shirley (New York) February 22, 2019 Check with publisher

    Defects in WNT3 are the cause of autosomal recessive tetra-amelia (ARTTRA). Tetra-amelia is a rare human genetic disorder characterized by complete absence of all four limbs and other anomalies such as craniofacial, nervous system, pulmonary, skeleta...

  • Wnt16 peptide

    Wnt16 peptide

    Biology & Physiology Shirley (New York) February 22, 2019 Check with publisher

    The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during em...

  • Wnt1 peptide

    Wnt1 peptide

    Pharmacology - Drug Development Shirley (New York) February 22, 2019 Check with publisher

    The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during em...

  • GLP In Vivo ADME & PK Studies

    GLP In Vivo ADME & PK Studies

    Biology & Physiology Shirley (New York) January 28, 2019 Check with publisher

    Thorough characterization and in-depth study of PK, as well as absorption, distribution, metabolism, and excretion (ADME) properties, are critical in order to support vaccine discovery and development processes for the production of safer and more ef...

  • Fully Synthetic Carbohydrate Based Cancer Vaccines

    Fully Synthetic Carbohydrate Based Cancer Vaccines

    Pharmacology - Drug Development Shirley (New York) January 28, 2019 Check with publisher

    Malignantly transformed cells often exhibit aberrant levels and types of cell surface carbohydrates, which are typically displayed as either glycoproteins or glycosphingolipids. Through exposure of the immune system to appropriately presented tumor a...

  • Suspension Culture for Avian Influenza Vaccine Production

    Suspension Culture for Avian Influenza Vaccine Production

    Molecular Biology Shirley (New York ) January 28, 2019 Check with publisher

    In recent years, animal cell culture technology has gradually replaced the traditional chick embryo production process for influenza vaccine production. Currently, most of cells applied for influenza vaccine production are adherent and grown as monol...

  • 2019 MIPS Requirements

    2019 MIPS Requirements

    Medical - Health Fremont (California) January 25, 2019 Check with publisher

    Overview: The Merit-based Incentive Payment System was created in Medicare to measure the performance of physicians and others serving Medicare payments in several areas, and adjust payments to those providers based on how they score in the program. ...

  • Treatment Planning for Mental Health Providers

    Treatment Planning for Mental Health Providers

    Medical - Health Fremont (California) January 25, 2019 Check with publisher

    Overview: Clinical treatment planning in any mental health setting is often thought of as a necessary routine that must be completed in order to provide a guide for patient course. Practitioners may treat the planning process with a cavalier approach...

  • MINA Peptide

    MINA Peptide

    Pharmacology - Drug Development Shirley (New York) January 22, 2019 Check with publisher

    MINA is a c-Myc (MYC; MIM 190080) target gene that may play a role in cell proliferation or regulation of cell growth. (Tsuneoka et al., 2002 [PubMed 12091391]; Zhang et al., 2005 [PubMed 15897898]). https://www.creative-diagnostics.com/MINA-Peptide-...

  • MD-2 Peptide

    MD-2 Peptide

    Molecular Biology Shirley (New York) January 22, 2019 Check with publisher

    This gene encodes a protein which associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccyaride (LPS), thus providing a link between the receptor and LPS signaling. Studies of the mouse ortholog suggest tha...

  • MAPKAP1 (AB1) Peptide

    MAPKAP1 (AB1) Peptide

    Molecular Biology Shirley (New York) January 22, 2019 Check with publisher

    This gene encodes a protein that is highly similar to the yeast SIN1 protein, a stress-activated protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been described. Alternate polyadenylation sites as well as alte...