Expertise

Premium listings
  • Expertise in genomics and transcriptomics

    Expertise in genomics and transcriptomics

    Data Analysis - Analytics August 24, 2015 Check with publisher

    I lead the Integrative Genomics of Ageing Group (http://pcwww.liv.ac.uk/~aging/), and I have extensive experience in data analysis and integration of multidimensional data. Although my lab’s research integrates different strategies, its focal point i...

Listings
  • Impurity Characterization and Management

    Impurity Characterization and Management

    Biology & Physiology Shirley (New York) September 30, 2019 Check with publisher

    Creative Biolabs has the experience of using analytical techniques to characterize impurities or contaminants and pays attention to the impurities that are called Potential Genotoxic Impurities (PGIs), which are known to be potential mutagens or carc...

  • Magic™ Humanized GITR Immune Checkpoint Knock-In Mice

    Magic™ Humanized GITR Immune Checkpoint Knock-In Mice

    Biology & Physiology Shirley (New York) September 30, 2019 Check with publisher

    Glucocorticoid-induced TNFR-related protein (GITR) or activation-inducible TNFR family receptor (AITR), which is also known as a member of the tumor necrosis factor receptor superfamily (member 18 as TNFRSF18), is currently of great interest to resea...

  • DNA Microinjection

    DNA Microinjection

    Biology & Physiology Shirley (New York) September 30, 2019 Check with publisher

    Microinjection is a useful technique that plays an important part in the generation of genetically modified mouse and rat models. Different microinjection systems can exist, the construction and configuration of which directly depends on the type of ...

  • Magic™ Humanized TNF-α Immune Checkpoint Knock-In Mice

    Magic™ Humanized TNF-α Immune Checkpoint Knock-In Mice

    Biology & Physiology Shirley (New York) September 30, 2019 Check with publisher

    Targeted immune checkpoint blockade augments anti-tumor immunity and induces durable responses in patients with melanoma and other solid tumors. Tumor necrosis factor (TNF or TNF-α) is a major pro-inflammatory cytokine involved in early The primary c...

  • Magic™ Humanized CD276 Immune Checkpoint Knock-In Mice

    Magic™ Humanized CD276 Immune Checkpoint Knock-In Mice

    Biology & Physiology Shirley (New York) September 30, 2019 Check with publisher

    Immune checkpoints refer to proteins that act as T cell receptor (TCR) co-signaling partners which deliver either positive or negative signals to T lymphocytes. Blocking the actions of the immune checkpoint receptors can produce a potent anti-tumor r...

  • Magic™ GPCR Stable Cell Lines For Antibody Function Study

    Magic™ GPCR Stable Cell Lines For Antibody Function Study

    Biology & Physiology Shirley (New York) September 30, 2019 Check with publisher

    Inspired by two signaling pathways involved in GPCR signaling pathways, Creative Biolabs has introduced an innovative anti-GPCR antibody function screening system in virtue of different fluorescent biosensor linked with the activity of 3 secondary me...

  • Magic™ cAMP-activated GPCR Cell Lines

    Magic™ cAMP-activated GPCR Cell Lines

    Biology & Physiology Shirley (New York) September 30, 2019 Check with publisher

    In currently days, G-protein coupled receptors (GPCRs) represent one class of the most popular therapeutic targets. To accelerate and simplify research of GPCR biology and drug discovery, Creative Biolabs has established an innovative Magic™ platform...

  • Magic™ DAG-activated GPCR Stable Cell Lines

    Magic™ DAG-activated GPCR Stable Cell Lines

    Biology & Physiology Shirley (New York) September 30, 2019 Check with publisher

    GPCRs transduce signals through a variety of cascades and elicit diverse biophysical activities. Therapeutic compounds targeting GPCRs (no matter biologics and small molecules) are designed to interfere with GPCR functionalities via activating (agoni...

  • Magic™ Calcium-activated GPCR Stable Cell Lines

    Magic™ Calcium-activated GPCR Stable Cell Lines

    Biology & Physiology Shirley (New York) September 30, 2019 Check with publisher

    Cell signaling networks are complicated, often composed of multiple pathways acting in concert to regulate particular cellular functions precisely. Receptors are the core components of the signaling pathway for receiving and transducing the signals. ...

  • Magic™ Humanized KDR Immune Checkpoint Knock-In Mice

    Magic™ Humanized KDR Immune Checkpoint Knock-In Mice

    Biology & Physiology Shirley (New York) September 30, 2019 Check with publisher

    Over the past decades, significant progress has been made in profiling the KDR (VEGFR-2) specific intracellular signaling cascades resulting in proliferation, migration, survival and increased permeability, all of which contribute to the angiogenic r...

  • Magic™ Humanized PD-L1/LAG-3 Dual Immune Checkpoint Knock-In Mice

    Magic™ Humanized PD-L1/LAG-3 Dual Immune Checkpoint Knock-In Mice

    Biology & Physiology Shirley (New York) September 30, 2019 Check with publisher

    LAG-3 (lymphocyte-activation gene 3), also named as CD223 (cluster of differentiation 223), is an immune checkpoint receptor expressed on the cell surface of effector T cells and regulatory T cells (Tregs), and functions as a co-inhibitory molecule t...

  • Magic™ Humanized PD-L1/TIGIT Dual Immune Checkpoint Knock-In Mice

    Magic™ Humanized PD-L1/TIGIT Dual Immune Checkpoint Knock-In Mice

    Biology & Physiology Shirley (New York) September 30, 2019 Check with publisher

    PD-L1 (Programmed death-ligand 1), also known as CD274 (cluster of differentiation 274) or B7-H1 (B7 homolog 1), is type 1 transmembrane protein expressed on the tumor cell surface, or on neighboring host immune cells in the tumor microenvironment. T...