Magic™ DAG-activated GPCR Stable Cell Lines

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  • Published date: September 30, 2019
    • Shirley, New York, United States

GPCRs transduce signals through a variety of cascades and elicit diverse biophysical activities. Therapeutic compounds targeting GPCRs (no matter biologics and small molecules) are designed to interfere with GPCR functionalities via activating (agonist) or blocking (antagonist) certain pathways. Hence, to characterize and understand the agonistic/antagonistic potentials against target GPCR is very critical for GPCR drug discovery. In order to address this demand, Creative Biolabs has launched a full portfolio of GPCR stable cell lines engineered with unique biosensor that can specifically link second messenger activation. https://www.creative-biolabs.com/drug-discovery/therapeutics/magic-dag-activated-gpcr-stable-cell-lines.htm .

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Jerry Carter
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