Anti-ITGAE (clone M290)-Mc-VC-PABC-MMAE ADC

  • 1.00 Dollar US$
  • Published date: December 8, 2018
    • Shirley, New York, United States

This ADC product is comprised of an anti-ITGAE monoclonal antibody (clone M290) conjugated via a Mc-VC-PABC linker to MMAE. The MMAE is targeted to certain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, MMAE binds to tubulins, interrupts microtubule dynamics, and subsequently, induces cell death. https://www.creative-biolabs.com/adc/target-itgae-59.htm

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Bella
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