Native Rhodococcus rhodochrous Epoxide Hydrolase

  • 1.00 Dollar US$
  • Published date: September 11, 2020
    • New York, New York, United States

Epoxide hydrolase (also known as epoxide hydratase) functions in detoxification during drug metabolism. It converts epoxides to trans-dihydrodiols, which can be conjugated and excreted from the body. Epoxides result from the degradation of aromatic compounds. Deficiency in this enzyme in patients receiving aromatic-type anti-epileptic drugs such as phenytoin is reported to lead to DRESS syndrome. Epoxides are significant as cytochrome P450 oxidase metabolites of unsaturated carbon-carbon bonds, but are also mutagenic. Epoxide hydrolase is present in large quantity on endoplasmic reticulum. https://www.creative-enzymes.com/product/Native-Rhodococcus-Rhodochrous-Epoxide-Hydrolase_1151.html

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