Magic™ Fluorogen Activating Protein (FAP) Assay for Internalization Assessment

  • Check with publisher
  • Published date: November 28, 2019
    • Shirley, New York, United States

Receptor-mediated endocytosis is an endocytotic process in which specific molecules are taken into the cell when binding to surface receptors. It is highly receptor-specific, and not all surface receptors are capable of triggering ligand internalization. Upon ligand binding, the ligand-receptor complex will diffuse through the plasma membrane until captured by a preformed or forming clathrin-coated pit. Some receptors can nucleate a clathrin-coated pit around the receptor. A mature pit will break away from the plasma membrane and from a clathrin-coated vesicle which then fusing to an early endosome. Once fused the endocytosed cargo (receptor and/or ligand) can then be sorted to lysosomal, recycling, or other trafficking pathways. https://www.creative-biolabs.com/drug-discovery/therapeutics/magic-fluorogen-activating-protein-fap-assay-for-internalization-assessment.htm .

Jerry Carter
0 votes

Useful information

  • Avoid scams by acting locally or paying with PayPal
  • Never pay with Western Union, Moneygram or other anonymous payment services
  • Don't buy or sell outside of your country. Don't accept cashier cheques from outside your country
  • This site is never involved in any transaction, and does not handle payments, shipping, guarantee transactions, provide escrow services, or offer "buyer protection" or "seller certification"

Related listings

  • Magic™ Humanized PD-1/LAG-3 Dual Immune Checkpoint Knock-In Mice

    Magic™ Humanized PD-1/LAG-3 Dual Immune Checkpoint Knock-In Mice

    Biological Sciences Shirley (New York) November 28, 2019 Check with publisher

    More and more evidence suggests that elevated expression of inhibitory receptors on tumor antigen-specific T cells is one of the mechanisms by which tumors evade host immune surveillance. Blockade of certain individual inhibitory receptor with specif...

  • Sleeping Beauty Transposon System

    Sleeping Beauty Transposon System

    Biological Sciences Shirley (New York) November 28, 2019 Check with publisher

    Sleeping Beauty (SB) transposon is a synthetic transposon of the Tc1-like mariner family. It was originally discovered in salmon, where it had been silenced through evolution and was then reconstructed by investigators based on molecular phylogenetic...

  • Tol2 Transposon System

    Tol2 Transposon System

    Biological Sciences Shirley (New York) November 28, 2019 Check with publisher

    The Tol2 transposon element was originally identified in the genome of the medaka fish and has now been extensively used to make transgenic zebrafish model for various studies. Afterward, this Tol2 transposon was discovered to be active in many other...