Fc Profiling Services

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  • Published date: October 30, 2019
    • Shirley, New York, United States

Antibody fragment crystallizable (Fc) region plays a critical part in eliciting indirect target elimination including ADCC, ADCP, CDC, all of which compose vital functioning mechanisms of most therapeutic antibodies. Over the past decade, Fc region is gaining increasing attention as a hot-spot for developing next-generation antibody drugs. Not only does it mediate various cytotoxic effector functions, but also it is closely related to the antibody in vivo half-life. Therefore, to in-depth validate the functional characteristics of Fc region is extremely important for estimating therapeutic potencies and pharmacokinetic behaviors of antibody candidates, before entering next stage. Creative Biolabs has established a versatile platform with a wide spectrum of assays, allowing for thoroughly studying of antibody Fc regions, and further optimization using multiple powerful engineering strategies. https://www.creative-biolabs.com/drug-discovery/therapeutics/fc-profiling-services.htm .

Jerry Carter
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