Light/Dark Box Test

  • Check with publisher
  • Published date: December 28, 2019
    • Shirley, New York, United States

The LDB test is a popular animal model used in pharmacology to assay unconditioned anxiety response in rodents. The LDB apparatus has two compartments. The large light compartment (2/3 of the box) is brightly lit and open, while the small dark compartment (1/3 of the box) is covered and dark. A door of 7 cm connects the two compartments. Rodents are placed in the middle of the brightly illuminated chamber and are allowed to move freely between the two chambers. They prefer darker areas, however, when presented in a novel environment, they have a tendency to explore. These two conflicting emotions lead to observable anxiety-like symptoms. When rodents are injected with anxiolytic drugs, time spent in the light compartment will increase. But when anxiogenic drugs are injected, more time is spent in the dark compartment. https://www.creative-biolabs.com/drug-discovery/therapeutics/light-dark-box-test.htm .

Jerry Carter
0 votes

Useful information

  • Avoid scams by acting locally or paying with PayPal
  • Never pay with Western Union, Moneygram or other anonymous payment services
  • Don't buy or sell outside of your country. Don't accept cashier cheques from outside your country
  • This site is never involved in any transaction, and does not handle payments, shipping, guarantee transactions, provide escrow services, or offer "buyer protection" or "seller certification"

Related listings

  • Other Motor Function Tests

    Other Motor Function Tests

    Biomedical Sciences Shirley (New York) December 28, 2019 Check with publisher

    The pole test evaluates the ability of the mouse to grasp and maneuver on a pole in order to descend to its home cage. Firstly, mice are trained to complete the pole task over two consecutive days. In the test session, mice are placed with their head...

  • Conditioned Place Preference

    Conditioned Place Preference

    Biomedical Sciences Shirley (New York) December 28, 2019 Check with publisher

    Conditioned place preference (CPP) is based on principles of Pavlovian classical conditioning, where the effect of the drug administered serves as the unconditioned stimulus (US) and is paired with the initially neutral environmental cues of the shut...

  • Marble Burying Test

    Marble Burying Test

    Biomedical Sciences Shirley (New York) December 28, 2019 Check with publisher

    A number of tests of anxiety in rodents have been developed to find out more about the biological bases of anxiety disorders and develop new, more efficient pharmacological and/or behavioral treatments. Particularly, Creative Biolabs utilizes the mar...