Magic™ Humanized CD86 Immune Checkpoint Knock-In Mice

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  • Published date: February 11, 2020
    • Shirley, New York, United States

The immune system should be able to generate an appropriate inflammatory response in order to effectively eliminate tumor cells. However, the fact that most of our immune cells contain a fail-safe mechanism to ensure they are not constantly activated is a double-edged sword. There are several markers found on both tumor cells and antigen presenting cells that can suppress or downregulate T cells once the corresponding ligand is bound. https://www.creative-biolabs.com/drug-discovery/therapeutics/magic-humanized-cd86-immune-checkpoint-knock-in-mice.htm .

Jerry Carter
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