Magic™ Humanized PD-1/PD-L1 Dual Immune Checkpoint Knock-In Mice

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  • Published date: October 30, 2019
    • Shirley, New York, United States

The therapy of using monoclonal antibodies against inhibitory receptors on immune cells, termed immune-checkpoint blockade, for the treatment of human cancer has gained a great deal of attention among clinicians, scientists, and patients. Checkpoint inhibitors have shown satisfactory efficacy in treatment for various human cancer. Immune checkpoint antibodies that augment the programmed cell death protein 1 (PD-1)/PD-L1 immune checkpoint pathway have shown antitumor activity across multiple malignancies. As a world leader in the industry of drug discovery, Creative Biolabs has successfully established a serious of Magic™ “humanized” animal models and can provide specialty humanized PD-1/PD-L1 dual immune checkpoint knock-in mice for our clients all over the world. .

Jerry Carter
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