Magic™ Humanized PD-1/TIM-3 Dual Immune Checkpoint Knock-In Mice

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  • Published date: October 30, 2019
    • Shirley, New York, United States

Co-inhibitory or immune checkpoint receptors have a key function in the maintenance of immune homeostasis: their expression on effector T cells allows the proper contraction of effector T cell responses and their expression on regulatory T (Treg) cells ensures the proper function of Treg cells to control effector T cells. Recently, the role of co-inhibitory receptors has come to the forefront in human cancer and chronic viral infection where these receptors are highly expressed and are being targeted clinically to improve anti-tumor and anti-viral T cell responses. As a world leader in the industry of anti-tumor drug discovery, Creative Biolabs has successfully launched a well-established Magic™ “humanized” animal platform to offer humanized PD-1/TIM-3 dual immune checkpoint knock-in mice for our worldwide clients. https://www.creative-biolabs.com/drug-discovery/therapeutics/magic-humanized-pd-1-tim-3-dual-immune-checkpoint-knock-in-mice.htm .

Jerry Carter
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