Ovariectomy (OVX)-Induced Osteoporosis in Rats

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  • Published date: October 30, 2019
    • Shirley, New York, United States

Osteoporosis is a disease characterized by low bone mass and structural deterioration of bone tissue, leading to bone fragility and an increased susceptibility to fractures. The incidence of osteoporosis increases with age and occurs most frequently in postmenopausal women due to the dramatic estrogen withdrawal associated with menopause. Animal models of postmenopausal bone loss induced with ovariectomy provided by Creative Biolabs present characteristics of bone loss and its sequelae resembles those found in postmenopausal women in some respects due to ovarian hormone deficiency. As a consequence, this model is widely applied for studying problems that are relevant to postmenopausal bone loss. https://www.creative-biolabs.com/drug-discovery/therapeutics/ovariectomy-ovx-induced-osteoporosis-in-rats.htm .

Jerry Carter
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