PEGylation

  • Check with publisher
  • Published date: February 11, 2019
    • Shirley, New York, United States

Polyethylene glycol (PEG) modification, also known as molecular PEGylation, is a promising technology developed in the late 1970s and widely used to improve delivery in pharmaceutical applications. Most chemical drugs and proteins, peptides and other biologic drugs have their own shortcomings. Linking the therapeutic protein or small molecules with suitable length of PEG chain can lead to an obviously change in the activity, molecular mass or other property. Moreover, the modification of polyethylene glycol molecules contributes to a less chance of contact between the drug and the protease, which can achieve the effect of half-life increasing and solubility enhancement for drug compounds. Meanwhile, the PEGylation is also supposed to be an efficient strategy to reduce the immunogenicity for most of exogenous material and improve the pharmacokinetic and pharmacodynamics properties. In this case, the PEG modification technology has attracted increasing attention of many scientists and pharmaceutical manufacturers.

BOC Sciences has been equipped with internationally advanced equipment, and professional and responsible personnel to provide comprehensive analysis and research to promote your project program. If you have any problems with polyvinyl alcohol modifiers and their modified drugs, please don't hesitate to contact us. Our staff are willing to serve you.

https://www.bocsci.com/solutions/pegylation.htm

Alex Brown
0 votes

Useful information

  • Avoid scams by acting locally or paying with PayPal
  • Never pay with Western Union, Moneygram or other anonymous payment services
  • Don't buy or sell outside of your country. Don't accept cashier cheques from outside your country
  • This site is never involved in any transaction, and does not handle payments, shipping, guarantee transactions, provide escrow services, or offer "buyer protection" or "seller certification"

Related listings

  • Telemedicine: Reimbursement Update

    Telemedicine: Reimbursement Update

    Clinical/Medical Sciences Fremont (California) March 3, 2020 Check with publisher

    Under the Social Security Act, reimbursement for telehealth under Medicare has been subject to stringent restrictions. Only patients in certain identified practice settings in rural, physician-underserved areas were eligible. Care into the patient's ...

  • HIPAA for Dummies (HIPAA Boot Camp)

    HIPAA for Dummies (HIPAA Boot Camp)

    Clinical/Medical Sciences Fremont (California) February 19, 2020 Check with publisher

    Overview: This lesson is going to get back to the basics using multiple real life scenarios and "what if's". My goal is to make this very confusing and not well explained law easy to understand for the typical staff member. I will uncover myths versu...

  • Legal Issues Raised by Deploying AI in Healthcare

    Legal Issues Raised by Deploying AI in Healthcare

    Clinical/Medical Sciences Fremont (California) February 19, 2020 Check with publisher

    Overview: Classically, the law reasons by analogy, and from precedent. The theory is that the law should deal with like situations in like ways. In some respects, however, Artificial Intelligence, especially the concept of machine learning, is virtua...