Cell Biology & Microbiology

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  • Pyrintegrin

    Pyrintegrin

    Cell Biology & Microbiology Shirley (New York) December 24, 2019 Check with publisher

    Pyrintegrin, a 2,4-disubstituted pyrimidine, enhances survival of human embryonic stem cells (hESCs) following enzymatic dissociation. Pyrintegrin increases the binding of the activated β1 integrin-specific antibody HUTS-21 and enhances the phosphory...

  • Gatifloxacin

    Gatifloxacin

    Cell Biology & Microbiology Shirley (New York) December 24, 2019 Check with publisher

    Gatifloxacin is a fluoroquinolone antibiotic, with potent activity against Gram-negative and Gram-positive bacteria. It also inhibits the bacterial enzymes DNA gyrase and topoisomerase IV. It was shown to promote self-renewal in human and mouse embry...

  • Stauprimide

    Stauprimide

    Cell Biology & Microbiology Shirley (New York) December 24, 2019 Check with publisher

    Stauprimide is an enhancer of embryonic stem cell differentiation into endoderm. It inhibits nuclear translocation of NME2. https://www.bocsci.com/stauprimide-cas-154589-96-5-item-263931.html

  • Fluoxetine hydrochloride

    Fluoxetine hydrochloride

    Cell Biology & Microbiology Shirley (New York) December 24, 2019 Check with publisher

    Fluoxetine hydrochloride is a selective serotonin-reuptake inhibitor (SSRI) at the neuronal membrane, and is used as an antidepressant. Fluoxetine exhibits strong inhibitory effects on both mineralization and adipogenesis in human mesenchymal stem ce...

  • Bucladesine Sodium Salt

    Bucladesine Sodium Salt

    Cell Biology & Microbiology Shirley (New York) December 24, 2019 Check with publisher

    Bucladesine sodium salt is a cell-permeable cAMP analog that activates cAMP dependent protein kinase (PKA) or the cAMP/PKA signaling pathway. It is used as a morphological differentiation inducer and cell signaling modulator in cells such as Schwann ...

  • Nicotinamide

    Nicotinamide

    Cell Biology & Microbiology Shirley (New York) December 24, 2019 Check with publisher

    Nicotinamide is a form of vitamin B3 obtained from processed food and vegetables, and a component of coenzymes NAD and NADP. Study demonstrated that it promoted survival and differentiation in human pluripotent stem cells (hPSCs) via inhibiting multi...

  • Genistein

    Genistein

    Cell Biology & Microbiology Shirley (New York) December 24, 2019 Check with publisher

    Genistein is a phytoestrogen found in soy products that acts as a protein tyrosine kinase (PTK) inhibitor. It inhibits breast cancer stem-like cells via downregulation of the Hedgehog-Gli1 signaling pathway. https://www.bocsci.com/genistein-cas-446-7...

  • Troglitazone

    Troglitazone

    Cell Biology & Microbiology Shirley (New York) December 24, 2019 Check with publisher

    Troglitazone is a potent PPARγ agonist with EC50 values of 0.55 and 0.78 µM for human and mouse, respectively. It is commonly used as an anti-diabetic and anti-inflammatory agent. It was shown to promote adipogenesis in 3T3-L1 cells. https://www.bocs...

  • Indomethacin

    Indomethacin

    Cell Biology & Microbiology Shirley (New York) December 24, 2019 Check with publisher

    Indomethacin is a COX inhibitor with IC50 values of 0.1 μg/mL and 5 μg/mL for COX1 and COX2, respectively. Indomethacin promotes adipogenesis of mesenchymal stem cell (MSC) via inhibition of COX2. https://www.bocsci.com/indomethacin-cas-53-86-1-item-...

  • Imatinib Mesylate

    Imatinib Mesylate

    Cell Biology & Microbiology Shirley (New York) December 24, 2019 Check with publisher

    Imatinib mesylate is a tyrosine kinase inhibitor. It was shown to maintain chronic myeloid leukemia stem cell potential in the absence of glucose. https://www.bocsci.com/imatinib-mesylate-cas-220127-57-1-item-473160.html

  • Kartogenin

    Kartogenin

    Cell Biology & Microbiology Shirley (New York) December 24, 2019 Check with publisher

    Kartogenin induces the selective differentiation of multipotent mesenchymal stem cells (MSCs) into chondrocytes. Kartogenin binds to filamin A, and disrupts the specific interaction between filamin A and CBFβ (core-binding factor β subunit). Apparent...

  • Raloxifene hydrochloride

    Raloxifene hydrochloride

    Cell Biology & Microbiology Shirley (New York) December 24, 2019 Check with publisher

    Raloxifene is a selective estrogen receptor modulator (SERM). Raloxifene can be used in the prevention of osteoporosis in postmenopausal women through inhibiting osteoclast differentiation. https://www.bocsci.com/raloxifene-hydrochloride-cas-82640-04...