Expertise
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Expertise in genomics and transcriptomics
Data Analysis - Analytics August 24, 2015 Check with publisherI lead the Integrative Genomics of Ageing Group (http://pcwww.liv.ac.uk/~aging/), and I have extensive experience in data analysis and integration of multidimensional data. Although my lab’s research integrates different strategies, its focal point i...
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FAQ Visa On Appearance (VOA)
Psychology Flumeri (AV) August 17, 2017 78.00 Pound £There are a number of websites that provide to arrange a charge on arrival for vietnam visa application, but the majority of among these are frauds. If you are planning to produce several check outs in Vietnam E Visa Online a brief period to Vietnam,...
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Physician Employment Agreements: Items to Consider
Pharmacology - Drug Development Fremont (California) October 22, 2019 Check with publisherOverview: We will review the various elements of the physician employment agreement, focusing on the pitfalls and the problems that can develop when the agreement does not clearly define the relationship, and/or when the parties do not fully understa...
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Drafting and Negotiating Physician Employment Contracts
Pharmacology - Drug Development Fremont (California) October 22, 2019 Check with publisherOverview: In this session Mr. Wolfe will provide practical guidance regarding physician employment contracts,including key regulatory requirements, key provisions and common compensation and common compensation models. Why should you Attend: Today th...
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Principles of Web Design for the Healthcare Industry
Pharmacology - Drug Development Fremont (California) October 10, 2019 Check with publisherOverview: A brief review of the basic principles of solid web design. Awareness of the possible compliance standards, including ADA, HIPAA, GDPR and FCC. Fundamentals of marketing: SEO, messaging, continuity Education on how to find the right experts...
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Magic™ Humanized PD-1 Immune Checkpoint Knock-In Mice
Biology & Physiology Shirley (New York) September 30, 2019 Check with publisherManagement of cancer is a big problem, not only because the difficulties in developing new drugs but also because tumor cells usually acquire resistance to anti-cancer drugs to avoid immune destruction (immune escape). One of the most important mecha...
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Magic™ Humanized LAG3 Immune Checkpoint Knock-In Mice
Biology & Physiology Shirley (New York) September 30, 2019 Check with publisherRecent achievements in cancer immunotherapy especially immune checkpoint modulators are reshaping the way of conventional cancer treatment. Nowadays, the rapid development of immune checkpoint targeting drugs has become one of the hotspots that are a...
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Magic™ Humanized OX40 Immune Checkpoint Knock-In Mice
Biology & Physiology Shirley (New York) September 30, 2019 Check with publisherAdministration of anti-OX40 increases proliferation of peripheral blood CD4+ and CD8+ T cells, increases responses to recall and naïve reporter Ags, and increases endogenous tumor-specific immune responses. Several agonistic anti-OX40 antibodies are ...
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Magic™ Humanized CD27 Immune Checkpoint Knock-In Mice
Biology & Physiology Shirley (New York) September 30, 2019 Check with publisherThe activity of CD27 is restricted by the transient availability of its ligand CD70/TNFSF7, which is constitutively expressed on medullary thymic epithelial cells (mTECs) and dendritic cells. Apart from this, CD70/TNFSF7 is specifically expressed aft...
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Magic™ Humanized SIRPα Immune Checkpoint Knock-In Mice
Biology & Physiology Shirley (New York) September 30, 2019 Check with publisherIn a wide variety of preclinical models, therapies that block the CD47/SIRPα axis stimulate phagocytosis of cancer cells in vitro and anti-tumor immune responses in vivo. Nowadays, many therapeutics targeting the CD47/SIRPα axis are under preclinical...
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Magic™ Humanized CD28 Immune Checkpoint Knock-In Mice
Biology & Physiology Shirley (New York) September 30, 2019 Check with publisherCD28 and CTLA4 are highly homologous and compete for the same ligands [B7-1 (CD80) and B7-2 (CD86)]. The affinity of CTLA4 binding to these ligands is higher than CD28, which enables CTLA4 to compete with CD28 for ligands and suppress effector T cell...
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Magic™ Humanized CD137 Immune Checkpoint Knock-In Mice
Biology & Physiology Shirley (New York) September 30, 2019 Check with publisherCD137 is one of the tumor necrosis factor (TNF) receptor family member, which is also known as TNFRSF9 and 4-1BB. CD137 is expressed on activated T cells, while to a larger extent on CD8+ than on CD4+ T cells. Additionally, CD137 is also found on den...
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Impurity Characterization and Management
Biology & Physiology Shirley (New York) September 30, 2019 Check with publisherCreative Biolabs has the experience of using analytical techniques to characterize impurities or contaminants and pays attention to the impurities that are called Potential Genotoxic Impurities (PGIs), which are known to be potential mutagens or carc...
