Biomedical Sciences

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  • DrugAge database of compounds that increase lifespan

    DrugAge database of compounds that increase lifespan

    Biomedical Sciences Liverpool August 24, 2015 Check with publisher

    We're starting a new database of drugs and compounds (including natural products) with anti-ageing properties that extend longevity in model organisms. The database will be called DrugAge, and although we have some data already, we are looking for da...

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  • Recombinant Human CD33 Protein(His tag), Biotinylated

    Recombinant Human CD33 Protein(His tag), Biotinylated

    Biomedical Sciences Shirley (New York) May 30, 2019 Check with publisher

    Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acid...

  • Recombinant Human CD38 Protein(Fc tag)

    Recombinant Human CD38 Protein(Fc tag)

    Biomedical Sciences Shirley (New York) May 30, 2019 Check with publisher

    Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the im...

  • DrugAge database of compounds that increase lifespan

    DrugAge database of compounds that increase lifespan

    Biomedical Sciences Liverpool (United Kingdom) August 24, 2015 Check with publisher

    We're starting a new database of drugs and compounds (including natural products) with anti-ageing properties that extend longevity in model organisms. The database will be called DrugAge, and although we have some data already, we are looking for da...

  • KPNA1 Peptide

    KPNA1 Peptide

    Biomedical Sciences Shirley (New York) January 22, 2019 Check with publisher

    The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective dif...

  • EPHB4   peptide

    EPHB4 peptide

    Biomedical Sciences Shirley (New York) June 25, 2019 Check with publisher

    Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchore...

  • Chicken Lactate Dehydrogenase

    Chicken Lactate Dehydrogenase

    Biomedical Sciences Shirley (New York) April 25, 2019 Check with publisher

    Plasmodium is a genus of parasitic protists. Infection by these organisms is known as malaria. The genus Plasmodium was described in 1885 by Ettore Marchiafava and Angelo Celli. Currently over 200 species of this genus are recognized and new species ...

  • GABRB3  peptide

    GABRB3 peptide

    Biomedical Sciences Shirley (New York) June 25, 2019 Check with publisher

    This gene encodes a member of the ligand-gated ionic channel family. The encoded protein is one the subunits of a multi-subunit chloride channel that serves as the receptor for gamma-aminobutyric acid, a major inhibitory neurotransmitter of the mamma...

  • MRE11 Peptide

    MRE11 Peptide

    Biomedical Sciences Shirley (New York) January 22, 2019 Check with publisher

    This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex...

  • HTR1A  peptide

    HTR1A peptide

    Biomedical Sciences Shirley (New York) June 25, 2019 Check with publisher

    This gene encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation ...

  • MBNL1  peptide

    MBNL1 peptide

    Biomedical Sciences Shirley (New York) June 25, 2019 Check with publisher

    MBNL1 (muscleblind-like splicing regulator 1) is a protein-coding gene. Diseases associated with MBNL1 include mixed malaria, and myotonic dystrophy type 2. GO annotations related to this gene include double-stranded RNA binding and RNA binding. An i...

  • Coupling Reaction

    Coupling Reaction

    Biomedical Sciences Shirley (New York) March 11, 2019 Check with publisher

    In general, coupling reaction is one of the reactions where two hydrocarbon fragments (or atoms) are coupled with the aid of catalyst. It is widely used in pharmaceutial industry. Cross-coupling reactions are those in which two different starting mat...

  • Reduction

    Reduction

    Biomedical Sciences Shirley (New York) March 11, 2019 Check with publisher

    Generally, reduction is the gain of electrons or a decrease in oxidation state by a molecule, atom, or ion. A reducing agent (also called a reductant or reducer) is an element (such as calcium) or compound that loses (or “donates”) an electron to ano...