Cell Biology & Microbiology

Listings

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  Enzyme Target & Activator & Inhibitor Screening Service

  Cell Biology & Microbiology Shirley (New York) March 29, 2019 Check with publisher

  Profacgen offers a comprehensive list of high-throughput screening services to specifically and efficiently identify potential enzyme substrates, activators and inhibitors. Enzymes participate in numerous physiological activities including signal tra...

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  Functional Complement Assays

  Cell Biology & Microbiology Shirley (New York) March 29, 2019 Check with publisher

  Profacgen provides a complete solution for complement function assays. The highly sensitive assays enable determination of specific activity of each of the three pathways separately without interference from the others. With years of experience, our ...

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  Technologies for Chiral Analysis and Separation

  Cell Biology & Microbiology Shirley (New York) April 1, 2019 Check with publisher

  Chiral compounds refer to enantiomers or diastereomers containing one or more asymmetric carbon chiral centers. In an achiral environment, the enantiomers have the same chemical properties (chemical reaction characteristics), the same physical proper...

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  Enantiomer Identification (HPLC/SFC)

  Cell Biology & Microbiology Shirley (New York) April 1, 2019 Check with publisher

  The analysis and identification of chiral compounds is one of the hot issues in the current analytical chemistry community. The chiral enantiomers are very similar in all aspects of their physical and chemical properties, so their separation is a dif...

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  Enantiomeric Purification (HPLC/SFC)

  Cell Biology & Microbiology Shirley (New York) April 1, 2019 Check with publisher

  The method for the purification of enantiomers by high performance liquid chromatography (HPLC) and supercritical fluid chromatography (SFC) is generally referred to as the continuous adsorption and desorption of compounds between the stationary phas...

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  Impurities Identification and Characterization

  Cell Biology & Microbiology Shirley (New York) April 1, 2019 Check with publisher

  Impurity profiling of a drug is an integral part to establish drug quality standards. According to the general guidelines stipulated by the International Conference to qualify the drug substance, the amount of acceptable level of each impurity should...

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  Protein Structure Modeling

  Cell Biology & Microbiology Shirley (New York) April 28, 2019 Check with publisher

  The three-dimensional structure of a protein provides essential information about its biological function and facilitates the design of therapeutic drugs that specifically bind to the protein target. Recent years have witnessed a tremendous increase ...

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  Protein Conjugation Service on Beads

  Cell Biology & Microbiology Shirley (New York) May 30, 2019 Check with publisher

  Profacgen provides protein conjugation service on beads to enable protein purification, precipitation, cell isolation, immunoassays and so on. Super paramagnetic beads can quickly gather in the magnetic field, while they can contribute to the separat...

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  Tranylcipromine

  Cell Biology & Microbiology Shirley (New York) December 24, 2019 Check with publisher

  Tranylcipromine inhibits Lysine-Specific Demethylase 1 (LSD1, IC50 = 20.7 µM), MAO A (IC50 = 2.3 µM) and MAO B (IC50 = 0.95 µM). This compound has been demonstrated that it promoted reprogramming of mouse embryonic fibroblasts to induced pluripotent ...

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  Azacitidine

  Cell Biology & Microbiology Shirley (New York) December 24, 2019 Check with publisher

  Azacitidine is a potent growth inhibitor and a cytotoxic agent. It acts as a demethylating agent by inhibiting DNA methyltransferase (Dnmt), forming covalent adducts with cellular DNMT1 depleting enzyme activity. It also improves the efficiency of re...

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  Vorinostat

  Cell Biology & Microbiology Shirley (New York) December 24, 2019 Check with publisher

  Vorinostat, a HDAC inhibitor, has been found to exhibit anti-angiogenic activity and could induce differentiation in breast cancer cells. https://www.bocsci.com/vorinostat-cas-149647-78-9-item-485286.html

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  Tacrolimus

  Cell Biology & Microbiology Shirley (New York) December 24, 2019 Check with publisher

  Tacrolimus is a calcineurin inhibitor immunosuppressant used for the treatment of patients with graft-versus-host disease (GVHD) after allogeneic hematopoietic stem cell transplantation (HSCT). https://www.bocsci.com/tacrolimus-cas-104987-11-3-item-4...