Project Offers - Collaborations

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  • DrugAge database of compounds that increase lifespan

    DrugAge database of compounds that increase lifespan

    Biomedical Sciences Liverpool August 24, 2015 Check with publisher

    We're starting a new database of drugs and compounds (including natural products) with anti-ageing properties that extend longevity in model organisms. The database will be called DrugAge, and although we have some data already, we are looking for da...

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  • Rodent Behavioral Tests for Cognition

    Rodent Behavioral Tests for Cognition

    Biomedical Sciences Shirley (New York) December 28, 2019 Check with publisher

    Cognition is a psychological term that includes the processes of learning, memory, and attention, as well as perception, language, intelligence, and reasoning. Cognitive phenomena are essentially internal psychological processes which, from the exper...

  • Light/Dark Box Test

    Light/Dark Box Test

    Biomedical Sciences Shirley (New York) December 28, 2019 Check with publisher

    The LDB test is a popular animal model used in pharmacology to assay unconditioned anxiety response in rodents. The LDB apparatus has two compartments. The large light compartment (2/3 of the box) is brightly lit and open, while the small dark compar...

  • Elevated Plus Maze Test

    Elevated Plus Maze Test

    Biomedical Sciences Shirley (New York) December 28, 2019 Check with publisher

    On the test day, rats or mice are placed at the junction of the four arms of the maze, facing an open arm. They prefer to stay in the closed arms than the open arms. The number of entries into the open arms and the time spent in each arm are recorded...

  • Elevated Plus Maze Test

    Elevated Plus Maze Test

    Biomedical Sciences Shirley (New York) December 28, 2019 Check with publisher

    On the test day, rats or mice are placed at the junction of the four arms of the maze, facing an open arm. They prefer to stay in the closed arms than the open arms. The number of entries into the open arms and the time spent in each arm are recorded...

  • Magic™ GLP1R Stable Cell Line

    Magic™ GLP1R Stable Cell Line

    Biomedical Sciences Shirley (New York) December 28, 2019 Check with publisher

    The glucagon-like peptide 1 receptor (GLP1R) is a member of the glucagon receptor family of G protein-coupled receptors. It is composed of two domains, one transmembrane (TMD) domain that binds the N-terminal region of GLP-1 and the extracellular (EC...

  • Magic™ GLP1R Stable Cell Line

    Magic™ GLP1R Stable Cell Line

    Biomedical Sciences Shirley (New York) December 28, 2019 Check with publisher

    The glucagon-like peptide 1 receptor (GLP1R) is a member of the glucagon receptor family of G protein-coupled receptors. It is composed of two domains, one transmembrane (TMD) domain that binds the N-terminal region of GLP-1 and the extracellular (EC...

  • Magic™ M5 Stable Cell Line

    Magic™ M5 Stable Cell Line

    Biomedical Sciences Shirley (New York) December 28, 2019 Check with publisher

    G protein-coupled receptors (GPCRs) play a crucial part in a variety of cellular physiological processes, which manifest as one popular therapeutic target for approximately 30%-40% current marketed drugs. Testing the function profiles of different co...

  • Pharmacokinetic Assays

    Pharmacokinetic Assays

    Biological Sciences Shirley (New York) November 28, 2019 Check with publisher

    Pharmacokinetics (PK) studies are of great importance in creating new therapeutic drugs, understanding both the beneficial and harmful effects of drugs, and guiding drug development experiments and trials. In PK assays, the applied assay method shoul...

  • Cassette Dosing Studies

    Cassette Dosing Studies

    Biological Sciences Shirley (New York) November 28, 2019 Check with publisher

    Cassette dosing is an efficient technique mainly applied in drug discovery efforts of pre-clinical studies, in order to obtain pharmacokinetic data from multiple candidate drugs in a single experiment. Thus, a similar amount of information obtained f...

  • In Vitro ADME

    In Vitro ADME

    Biological Sciences Shirley (New York) November 28, 2019 Check with publisher

    Creative Biolabs offers services in the application of in vitro experimental systems to evaluate drug absorption, distribution, metabolism, and excretion. Based on our state-of-the-art research, we seek to develop drugs by ADME studies. We are able t...

  • Mode of Action (MOA) Determination for Fungi

    Mode of Action (MOA) Determination for Fungi

    Biological Sciences Shirley (New York) November 28, 2019 Check with publisher

    Recent antifungal drugs have many side effects which limit their clinical use. For instance, amphotericin B has severe acute and chronic toxicities, and azoles have a low susceptibility to fungal pathogens. To improve drugs' efficiency and reduce the...

  • In Vitro Pharmacodynamics

    In Vitro Pharmacodynamics

    Biological Sciences Shirley (New York) November 28, 2019 Check with publisher

    Pharmacodynamics (PD) is the study of the biochemical, physiologic, and molecular effects of drugs on the body, and involves receptor binding, post-receptor effects, and chemical interactions. It is a study of how the drug affects the organism. It de...