Project Offers - Collaborations

Premium listings
  • DrugAge database of compounds that increase lifespan

    DrugAge database of compounds that increase lifespan

    Biomedical Sciences Liverpool August 24, 2015 Check with publisher

    We're starting a new database of drugs and compounds (including natural products) with anti-ageing properties that extend longevity in model organisms. The database will be called DrugAge, and although we have some data already, we are looking for da...

Listings
  • DrugAge database of compounds that increase lifespan

    DrugAge database of compounds that increase lifespan

    Biomedical Sciences Liverpool (United Kingdom) August 24, 2015 Check with publisher

    We're starting a new database of drugs and compounds (including natural products) with anti-ageing properties that extend longevity in model organisms. The database will be called DrugAge, and although we have some data already, we are looking for da...

  • Apoptosis and Programmed Cell Death Assessment

    Apoptosis and Programmed Cell Death Assessment

    Biomedical Sciences Shirley (New York) October 30, 2019 Check with publisher

    Apoptosis is a type of programmed cell death (PCD), which is defined as a highly regulated process of cell elimination. Key events of apoptotic cells involve cell shrinking, nuclear and chromosomal fragmentation, PARP cleavage, etc. Two major pathway...

  • Endocytosis and Internalization Potency Detection

    Endocytosis and Internalization Potency Detection

    Biomedical Sciences Shirley (New York) October 30, 2019 Check with publisher

    One important mechanism of action of therapeutic antibodies is to induce internalization and turnover of cell surface receptors, resulting in receptor down-modulation as well as antibody endocytosis. This receptor-mediated internalization exhibits gr...

  • Light/Dark Box Test

    Light/Dark Box Test

    Biomedical Sciences Shirley (New York) October 30, 2019 Check with publisher

    Creative Biolabs conducts a battery of anxiety behavioral tests to evaluate the potential therapeutic value and the anxiolytic activity of novel compounds. Specifically, the light/dark box test (LDB) is based on the innate aversion of rodents to brig...

  • Peptide Analysis Services

    Peptide Analysis Services

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    Peptides are a general term for biologically active substances involved in various cellular functions in living organisms, and are often used in functional analysis, antibody research, and especially in drug development. In order to apply peptides be...

  • Stapled Peptide Synthesis

    Stapled Peptide Synthesis

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    Stapled peptide is a full-carbon scaffold with an α-helical structure. The all-carbon scaffold stabilizes the α-helical structure, enhances the interaction between the peptide molecule and the protein, and the peptide can pass through the cell membra...

  • Cyclic Peptide synthesis

    Cyclic Peptide synthesis

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    Cyclic peptide compounds are a class of cyclic compounds with special structure, widely biological activity and unique mechanism of action, which play an important role in natural products. Cyclic peptides are compounds of stable and uniform conforma...

  • Peptide PEGylation

    Peptide PEGylation

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    It has long been a dream in medicine and pharmacy to use peptides and proteins as drugs. The driving force for this interest is the ability of these compounds to eliminate toxic or overproduced compounds in the body and to mimic endogenous hormones, ...

  • Amination

    Amination

    Biomedical Sciences Shirley (New York) March 11, 2019 Check with publisher

    Amination is the reaction process of introducing amine groups (-NH2) into organic molecules to form amines. Amines as a very potent drug functional group exist in most drug structures. For example, cyclized amines are considered to be the pharmacopho...

  • Parallel Artificial Membrane Permeability Assay (PAMPA)

    Parallel Artificial Membrane Permeability Assay (PAMPA)

    Biomedical Sciences Shirley (New York) October 30, 2019 Check with publisher

    Passive diffusion is an important way for drug absorption. It influences drugs pass through the intestinal epithelium, the blood brain barrier or transport across cell membranes. The PAMPA model is an artificial in vitro model suitable for the passiv...

  • Fc Profiling Services

    Fc Profiling Services

    Biomedical Sciences Shirley (New York) October 30, 2019 Check with publisher

    Antibody fragment crystallizable (Fc) region plays a critical part in eliciting indirect target elimination including ADCC, ADCP, CDC, all of which compose vital functioning mechanisms of most therapeutic antibodies. Over the past decade, Fc region i...

  • Interference with Nucleic Acid Synthesis

    Interference with Nucleic Acid Synthesis

    Biomedical Sciences Shirley (New York) October 30, 2019 Check with publisher

    Gene is the manipulator of life. It consists of a large number of nucleic acids and is responsible for the direction of metabolism throughout the life of a cell. They direct the synthesis of protein, control the production of enzymes, and are respons...