Project Offers - Collaborations

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  • DrugAge database of compounds that increase lifespan

    DrugAge database of compounds that increase lifespan

    Biomedical Sciences Liverpool August 24, 2015 Check with publisher

    We're starting a new database of drugs and compounds (including natural products) with anti-ageing properties that extend longevity in model organisms. The database will be called DrugAge, and although we have some data already, we are looking for da...

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  • DrugAge database of compounds that increase lifespan

    DrugAge database of compounds that increase lifespan

    Biomedical Sciences Liverpool (United Kingdom) August 24, 2015 Check with publisher

    We're starting a new database of drugs and compounds (including natural products) with anti-ageing properties that extend longevity in model organisms. The database will be called DrugAge, and although we have some data already, we are looking for da...

  • Physicochemical Characterization

    Physicochemical Characterization

    Biomedical Sciences Shirley (New York) January 15, 2020 Check with publisher

    Physicochemical properties of drugs include the aspects of ionization, stability, lipophilicity, solubility, hydrogen bonding, molecular size, etc. Understanding and optimizing the physicochemical properties of compounds are the fundamental for drug ...

  • Antifungal Synergistic and Antagonistic Effects Testing

    Antifungal Synergistic and Antagonistic Effects Testing

    Biomedical Sciences Shirley (New York) October 30, 2019 Check with publisher

    Novel drugs and/or new approaches to combat infective fungi and overcome fungal resistance are urgently needed. Pay attention to the interactions between different drugs is an economical method. Creative Biolabs provides in vitro assays to measure th...

  • Time-Kill Analysis for Fungi

    Time-Kill Analysis for Fungi

    Biomedical Sciences Shirley (New York) January 15, 2020 Check with publisher

    Time-kill curve assay is a broth-based method, and the rate of killing a fixed inoculum fungus is determined by comparing control group (no drug) and experiment group (antimicrobial agent-containing). The kill curves are constructed by plotting the C...

  • Apoptosis and Programmed Cell Death Assessment

    Apoptosis and Programmed Cell Death Assessment

    Biomedical Sciences Shirley (New York) October 30, 2019 Check with publisher

    Apoptosis is a type of programmed cell death (PCD), which is defined as a highly regulated process of cell elimination. Key events of apoptotic cells involve cell shrinking, nuclear and chromosomal fragmentation, PARP cleavage, etc. Two major pathway...

  • Drug Repurposing

    Drug Repurposing

    Biomedical Sciences Shirley (New York) January 15, 2020 Check with publisher

    In silico drug repositioning refers to utilize online public databases and bioinformatics tools to identify interaction networks between drugs and targets. As years of accumulation of structure information of proteins and therapeutic compounds, Creat...

  • Endocytosis and Internalization Potency Detection

    Endocytosis and Internalization Potency Detection

    Biomedical Sciences Shirley (New York) October 30, 2019 Check with publisher

    One important mechanism of action of therapeutic antibodies is to induce internalization and turnover of cell surface receptors, resulting in receptor down-modulation as well as antibody endocytosis. This receptor-mediated internalization exhibits gr...

  • Light/Dark Box Test

    Light/Dark Box Test

    Biomedical Sciences Shirley (New York) December 28, 2019 Check with publisher

    The LDB test is a popular animal model used in pharmacology to assay unconditioned anxiety response in rodents. The LDB apparatus has two compartments. The large light compartment (2/3 of the box) is brightly lit and open, while the small dark compar...

  • Light/Dark Box Test

    Light/Dark Box Test

    Biomedical Sciences Shirley (New York) October 30, 2019 Check with publisher

    Creative Biolabs conducts a battery of anxiety behavioral tests to evaluate the potential therapeutic value and the anxiolytic activity of novel compounds. Specifically, the light/dark box test (LDB) is based on the innate aversion of rodents to brig...

  • Elevated Plus Maze Test

    Elevated Plus Maze Test

    Biomedical Sciences Shirley (New York) December 28, 2019 Check with publisher

    On the test day, rats or mice are placed at the junction of the four arms of the maze, facing an open arm. They prefer to stay in the closed arms than the open arms. The number of entries into the open arms and the time spent in each arm are recorded...

  • Peptide Analysis Services

    Peptide Analysis Services

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    Peptides are a general term for biologically active substances involved in various cellular functions in living organisms, and are often used in functional analysis, antibody research, and especially in drug development. In order to apply peptides be...

  • Magic™ Humanized PD-1/OX40 Dual Immune Checkpoint Knock-In Mice

    Magic™ Humanized PD-1/OX40 Dual Immune Checkpoint Knock-In Mice

    Biomedical Sciences Shirley (New York) February 11, 2020 Check with publisher

    Even though immunotherapy has shown great potential in improving outcomes for patients with cancer, particularly through a combination of agents targeting immune inhibitory pathways, how to optimally combine the many new immunotherapy agents being de...