Project Offers - Collaborations
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DrugAge database of compounds that increase lifespan
Biomedical Sciences Liverpool August 24, 2015 Check with publisherWe're starting a new database of drugs and compounds (including natural products) with anti-ageing properties that extend longevity in model organisms. The database will be called DrugAge, and although we have some data already, we are looking for da...
Listings
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DrugAge database of compounds that increase lifespan
Biomedical Sciences Liverpool (United Kingdom) August 24, 2015 Check with publisherWe're starting a new database of drugs and compounds (including natural products) with anti-ageing properties that extend longevity in model organisms. The database will be called DrugAge, and although we have some data already, we are looking for da...
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Antifungal Synergistic and Antagonistic Effects Testing
Biomedical Sciences Shirley (New York) October 30, 2019 Check with publisherNovel drugs and/or new approaches to combat infective fungi and overcome fungal resistance are urgently needed. Pay attention to the interactions between different drugs is an economical method. Creative Biolabs provides in vitro assays to measure th...
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Apoptosis and Programmed Cell Death Assessment
Biomedical Sciences Shirley (New York) October 30, 2019 Check with publisherApoptosis is a type of programmed cell death (PCD), which is defined as a highly regulated process of cell elimination. Key events of apoptotic cells involve cell shrinking, nuclear and chromosomal fragmentation, PARP cleavage, etc. Two major pathway...
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Endocytosis and Internalization Potency Detection
Biomedical Sciences Shirley (New York) October 30, 2019 Check with publisherOne important mechanism of action of therapeutic antibodies is to induce internalization and turnover of cell surface receptors, resulting in receptor down-modulation as well as antibody endocytosis. This receptor-mediated internalization exhibits gr...
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Light/Dark Box Test
Biomedical Sciences Shirley (New York) October 30, 2019 Check with publisherCreative Biolabs conducts a battery of anxiety behavioral tests to evaluate the potential therapeutic value and the anxiolytic activity of novel compounds. Specifically, the light/dark box test (LDB) is based on the innate aversion of rodents to brig...
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Peptide Analysis Services
Biological Sciences Shirley (New York) July 18, 2019 Check with publisherPeptides are a general term for biologically active substances involved in various cellular functions in living organisms, and are often used in functional analysis, antibody research, and especially in drug development. In order to apply peptides be...
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Stapled Peptide Synthesis
Biological Sciences Shirley (New York) July 18, 2019 Check with publisherStapled peptide is a full-carbon scaffold with an α-helical structure. The all-carbon scaffold stabilizes the α-helical structure, enhances the interaction between the peptide molecule and the protein, and the peptide can pass through the cell membra...
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Pharmacokinetic Assays
Biological Sciences Shirley (New York) November 28, 2019 Check with publisherPharmacokinetics (PK) studies are of great importance in creating new therapeutic drugs, understanding both the beneficial and harmful effects of drugs, and guiding drug development experiments and trials. In PK assays, the applied assay method shoul...
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Cyclic Peptide synthesis
Biological Sciences Shirley (New York) July 18, 2019 Check with publisherCyclic peptide compounds are a class of cyclic compounds with special structure, widely biological activity and unique mechanism of action, which play an important role in natural products. Cyclic peptides are compounds of stable and uniform conforma...
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In Vitro ADME
Biological Sciences Shirley (New York) November 28, 2019 Check with publisherCreative Biolabs offers services in the application of in vitro experimental systems to evaluate drug absorption, distribution, metabolism, and excretion. Based on our state-of-the-art research, we seek to develop drugs by ADME studies. We are able t...
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Peptide PEGylation
Biological Sciences Shirley (New York) July 18, 2019 Check with publisherIt has long been a dream in medicine and pharmacy to use peptides and proteins as drugs. The driving force for this interest is the ability of these compounds to eliminate toxic or overproduced compounds in the body and to mimic endogenous hormones, ...
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In Vitro Pharmacodynamics
Biological Sciences Shirley (New York) November 28, 2019 Check with publisherPharmacodynamics (PD) is the study of the biochemical, physiologic, and molecular effects of drugs on the body, and involves receptor binding, post-receptor effects, and chemical interactions. It is a study of how the drug affects the organism. It de...
