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DrugAge database of compounds that increase lifespan
Biomedical Sciences Liverpool August 24, 2015 Check with publisherWe're starting a new database of drugs and compounds (including natural products) with anti-ageing properties that extend longevity in model organisms. The database will be called DrugAge, and although we have some data already, we are looking for da...
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Peptide Drug Bioconjugations
Drug Development Shirley (New York) January 11, 2019 Check with publisherBioconjugation is a chemical strategy to form a stable covalent link between two molecules, at least one of which is a biomolecule. The field of bioconjugation has had a considerable impact on academic research, clinical diagnostics and the productio...
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GMP Service
Cell Biology & Microbiology Shirley (New York) January 11, 2019 Check with publisherPeptides have inherent properties such as high biological activity, low toxicity, and high specificity. Peptides are now increasingly used in clinical research. A number of peptide drugs are already on the market, and hundreds more are at different s...
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Chiral Building Blocks
Chemical Methods Shirley (New York) January 10, 2019 Check with publisherBuilding block is a term in chemistry which is used to describe a virtual molecular fragment or a real chemical compound the molecules of which possess reactive functional groups. As for chiral building blocks, they are valuable intermediates in the ...
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Chiral Synthesis
Chemical Methods Shirley (New York) January 10, 2019 Check with publisherChiral synthesis, is also called enantioselective synthesis, plays an essential role in the discovery of innovative drugs and materials and has been widely used in the development of pharmaceutical products and other biologically active substances. F...
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Metabolites Synthesis
Drug Development Shirley (New York) January 10, 2019 Check with publisherMetabolites of pharmaceutical compounds are pivotal to comprehending drug metabolism, potential drug interactions, and human drug metabolizing enzymes. Primary metabolites are synthesized by the cell because they are critical for biological growth li...
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Intermediates Synthesis
Drug Development Shirley (New York) January 10, 2019 Check with publisherOwing to chirality is a pivotal factor in the safety and efficacy of many drug products, the production of single enantiomers of drug intermediates has become increasingly important in the pharmaceuticals industry. It has been seen that the increasin...
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Building Block Synthesis
Drug Development Shirley (New York) January 10, 2019 Check with publisherDuring the last decades, the synthesis of building blocks has been explored by numerous groups, which are used in pharmaceutical products and other biologically active substances. Building blocks are important intermediates for many drugs and have ma...
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Hit to Lead
Drug Development Shirley (New York) January 10, 2019 Check with publisherHit to Lead also known as lead generation is a prerequisite for the construction of new drugs’ molecular structures and the key first step in the development of new drugs. This stage aims to obtain each hit series and try to produce more potent and s...
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Lead Discovery
Bioinformatics - Data Analysis Shirley (New York) January 10, 2019 Check with publisherPharmaceutical development is an extreme complex process, involves discovery of innovative active ingredients and launch of a finished product, which always take more than ten years and enormous cost. The discovery of lead compounds are the initial r...
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Library Design
Drug Development Shirley (New York) January 10, 2019 Check with publisherA well-designed compound library contains a broad range of truly stored chemicals and/or virtual compounds, which can meet majority requirements and truly jump-start the search for new drugs. In addition, such compound library or chemical library is ...
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Medicinal chemistry
Drug Development Shirley (New York) January 10, 2019 Check with publisherMedicinal chemistry is an integrated discipline which links many scientific fields in researching and developing new drugs. Medicinal chemistry deals with the design, optimization and development of chemical compounds for use as drugs. It is inherent...
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Promotion and Advertising Practices - FDA Scrutiny 2019
Training and Teaching California (SFO) November 29, 2018 FreeDescription: If you go "off label" with advertising and promotion, FDA's hammer can hit hard and seemingly out of the blue. Advertising and promotion for devices is weak and lacks legal clarity. For drugs, the regulations are prescriptive and guidanc...
