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  • DrugAge database of compounds that increase lifespan

    DrugAge database of compounds that increase lifespan

    Biomedical Sciences Liverpool August 24, 2015 Check with publisher

    We're starting a new database of drugs and compounds (including natural products) with anti-ageing properties that extend longevity in model organisms. The database will be called DrugAge, and although we have some data already, we are looking for da...

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  • Endotoxin Removal Kits

    Endotoxin Removal Kits

    Reagents - Supplies Shirley (New York) October 28, 2020 Check with publisher

    Endotoxin removal kits are designed to efficiently remove endotoxin contamination from biological samples. It is suitable for the endotoxin removal of protein samples, monoclonal antibody drugs, therapeutic vaccines, small molecule chemical drugs, ot...

  • Epigenetic Assays

    Epigenetic Assays

    Laboratory Equipment and Instrumentation Shirley (New York) October 28, 2020 Check with publisher

    Acetylation of histones including histone H3 has been involved in the regulation of chromatin structure and recruitment of transcription factors to the gene promoters. Histone acetyltransfeases (HAT) and histone deacetylases (HDACs) play a critical r...

  • Recombinant SARS-CoV-2 papain-like protease [His]

    Recombinant SARS-CoV-2 papain-like protease [His]

    Immunology Shirley (New York) October 19, 2020 Check with publisher

    The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. PLpro has the additional function of stripping ubiquitin and ISG15 fr...

  • Recombinant SARS-CoV-2 NSP1 [His]

    Recombinant SARS-CoV-2 NSP1 [His]

    Immunology Shirley (New York) October 19, 2020 Check with publisher

    The Severe Acute Respiratory Syndrome (SARS) Coronavirus (CoV) is an enveloped, positive-stranded RNA viruses that can cause a severe respiratory disease. Its genome consists of a ∼30 kb linear, non-segmented, capped, polycistronic, polyadenylated RN...

  • ANDA Submission and GDUFA Guidance

    ANDA Submission and GDUFA Guidance

    Drug Development Palo Alto (California) September 22, 2020 329.00 Dollar US$

    In order to properly, effectively, and efficiently bring generic drugs and medicinal products to market, it is crucial to anyone interacting with the submittal process to understand how the process is structured and functions

  • Nitroreductase from Escherichia coli, Recombinant

    Nitroreductase from Escherichia coli, Recombinant

    Reagents - Supplies New York (New York) September 11, 2020 1.00 Dollar US$

    Nitroreductase increases the sensitivity of organisms to nitro-containing drugs such as metronidazole by converting the nitro group to a cytotoxic nitro radical. Shows ability to reduce quinines. Enzyme for activating prodrugs in antibody directed en...

  • Native Rhodococcus rhodochrous Epoxide Hydrolase

    Native Rhodococcus rhodochrous Epoxide Hydrolase

    Reagents - Supplies New York (New York) September 11, 2020 1.00 Dollar US$

    Epoxide hydrolase (also known as epoxide hydratase) functions in detoxification during drug metabolism. It converts epoxides to trans-dihydrodiols, which can be conjugated and excreted from the body. Epoxides result from the degradation of aromatic c...

  • Lipophilicity

    Lipophilicity

    Drug Development Shirley (New York) August 24, 2020 Check with publisher

    Creative Biolabs provides a number of experimental protocols to determine lipophilicity for drugs. https://www.creative-biolabs.com/drug-discovery/therapeutics/lipophilicity.htm

  • Antifungal Synergistic and Antagonistic Effects Testing

    Antifungal Synergistic and Antagonistic Effects Testing

    Drug Development Shirley (New York) August 24, 2020 Check with publisher

    Creative Biolabs provides in vitro assays to measure the effect of combined drugs for fungal activities in the ways of synergistic and antagonistic. https://www.creative-biolabs.com/drug-discovery/therapeutics/antifungal-synergistic-and-antagonistic-...

  • T 705

    T 705

    Drug Development Shirley (New York) August 4, 2020 Check with publisher

    Favipiravir, also known as T-705 or Avigan, is an experimental antiviral drug being developed by Toyama Chemical of Japan with activity against many RNA viruses. Like some other experimental antiviral drugs (T-1105 and T-1106), it is a pyrazinecarbox...

  • Self-setting calcium phosphate cement (CPC)

    Self-setting calcium phosphate cement (CPC)

    Reagents - Supplies Bohemia (NY ) July 31, 2020 Check with publisher

    The main composition of CPC is amorphous HAP. CPC has excellent biocompatibility. It can be easily absorbed in vivo. Degradation is equal to the formation of new bone. Its main properties are as follows: (1) Easy shaping and handling; (2) Self-settin...

  • Native Avian myeloblastosis virus AMV-Reverse Transcriptase

    Native Avian myeloblastosis virus AMV-Reverse Transcriptase

    Reagents - Supplies New York (New York) July 9, 2020 1.00 Dollar US$

    A Reverse transcriptase (RT) is an enzyme used to geneRate complementary DNA (cDNA) from an RNA template, a process termed reverse transcription. It is mainly associated with retroviruses. However, non-retroviruses also use RT (for example, the hepat...