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  • DrugAge database of compounds that increase lifespan

    DrugAge database of compounds that increase lifespan

    Biomedical Sciences Liverpool August 24, 2015 Check with publisher

    We're starting a new database of drugs and compounds (including natural products) with anti-ageing properties that extend longevity in model organisms. The database will be called DrugAge, and although we have some data already, we are looking for da...

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  • Peptide Glycosylation

    Peptide Glycosylation

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    On the basis of extensive experience in peptide synthesis, Creative Peptides proudly offers the most comprehensive glycopeptides synthesis services to our worldwide clients. Our scientists are committed to deliver high quality glycopeptides which wil...

  • Peptide Phosphorylation

    Peptide Phosphorylation

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    Phosphorylation is a ubiquitous and essential post-translational modification (PTM) by covalent addition of a phosphate (PO43−) group to a protein or other organic molecule. Phosphorylation of peptides is the most common and important method of post-...

  • Peptide Lead Optimization

    Peptide Lead Optimization

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    Peptide lead optimization is to improve upon a lead molecule that demonstrates activity at a target of interest by optimizing its potency or selectivity at the target and its absorption, distribution, metabolism and elimination (ADME) properties. For...

  • Peptide Drug Discovery

    Peptide Drug Discovery

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    Peptide drug refers to a peptide having a specific therapeutic effect extracted by chemical synthesis, genetic recombination or animal or plant, and is a specific application of the peptide in the field of medicine. The biological activity of the pep...

  • Oligopeptide Synthesis

    Oligopeptide Synthesis

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    Oligopeptides, also known as small peptides, are bioactive peptides composed of 2-10 amino acid residues linked by peptide bonds. Numerous studies have shown that proteins are eventually absorbed in the form of oligopeptides and amino acids, and that...

  • Long Peptides Synthesis

    Long Peptides Synthesis

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    Many studies require the use of peptides with more than 50 to 150 amino acids. Researches have also shown that synthetic long peptide-binding adjuvants have been widely used in cancer therapeutic vaccine research. In the traditional sense, more than ...

  • Stapled Peptide Synthesis

    Stapled Peptide Synthesis

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    Stapled peptide is a full-carbon scaffold with an α-helical structure. The all-carbon scaffold stabilizes the α-helical structure, enhances the interaction between the peptide molecule and the protein, and the peptide can pass through the cell membra...

  • Peptoid Synthesis

    Peptoid Synthesis

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    Peptoids, or poly-N-substituted glycines, are a class of peptidomimetics whose side chains are appended to the nitrogen atom of the peptide backbone, rather than to the α-carbons (as they are in amino acids). Notably, peptoids lack the amide hydrogen...

  • Recombinant Peptide Synthesis

    Recombinant Peptide Synthesis

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    For many years, chemical synthesis of large peptides and proteins has been a daunting task. The expansive progression in different ligation methods assists in the successful fulfillment of this large order. Since the building blocks can be obtained e...

  • Antigen Peptides

    Antigen Peptides

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    Peptide antigen, namely, a peptide used to trigger animal's immune system to develop antibodies specific to that peptide. Nowadays, the use of synthetic peptide antigens as immunogens has markedly increased, and this technique is also widely applied ...

  • Stapled Peptide Design

    Stapled Peptide Design

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    Peptide stapling is a strategy for constraining short peptides typically in an alpha-helical conformation. Stapling is carried out by covalently linking the side-chains of two amino acids, thereby forming a peptide macrocycle. Peptide “stapling” via ...

  • Peptide Library Design

    Peptide Library Design

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    Our technical and applications support team can offer advice on library design and experimental set up and analysis. Relating to design, we can advise on the best overlap or offset of peptides to be used in your target application, and then using you...