Project Offers - Collaborations

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  • DrugAge database of compounds that increase lifespan

    DrugAge database of compounds that increase lifespan

    Biomedical Sciences Liverpool August 24, 2015 Check with publisher

    We're starting a new database of drugs and compounds (including natural products) with anti-ageing properties that extend longevity in model organisms. The database will be called DrugAge, and although we have some data already, we are looking for da...

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  • Peptoid Synthesis

    Peptoid Synthesis

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    Peptoids, or poly-N-substituted glycines, are a class of peptidomimetics whose side chains are appended to the nitrogen atom of the peptide backbone, rather than to the α-carbons (as they are in amino acids). Notably, peptoids lack the amide hydrogen...

  • Recombinant Peptide Synthesis

    Recombinant Peptide Synthesis

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    For many years, chemical synthesis of large peptides and proteins has been a daunting task. The expansive progression in different ligation methods assists in the successful fulfillment of this large order. Since the building blocks can be obtained e...

  • Antigen Peptides

    Antigen Peptides

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    Peptide antigen, namely, a peptide used to trigger animal's immune system to develop antibodies specific to that peptide. Nowadays, the use of synthetic peptide antigens as immunogens has markedly increased, and this technique is also widely applied ...

  • Stapled Peptide Design

    Stapled Peptide Design

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    Peptide stapling is a strategy for constraining short peptides typically in an alpha-helical conformation. Stapling is carried out by covalently linking the side-chains of two amino acids, thereby forming a peptide macrocycle. Peptide “stapling” via ...

  • Peptide Library Design

    Peptide Library Design

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    Our technical and applications support team can offer advice on library design and experimental set up and analysis. Relating to design, we can advise on the best overlap or offset of peptides to be used in your target application, and then using you...

  • De novo Peptide Design

    De novo Peptide Design

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    De novo design is an attractive approach for constructing designed peptides with predetermined structures and functions. Creative Peptides provides de novo design related services for peptides engineering, including peptides structure prediction, pep...

  • Peptide Design

    Peptide Design

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    Interested in the use of biologically active proteins and peptides as potential therapeutic agents has grown dramatically in recent years. Although many meaningful studies can be performed, it is important to consider several factors such as the leng...

  • Cyclic Peptide synthesis

    Cyclic Peptide synthesis

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    Cyclic peptide compounds are a class of cyclic compounds with special structure, widely biological activity and unique mechanism of action, which play an important role in natural products. Cyclic peptides are compounds of stable and uniform conforma...

  • Cyclic Peptides

    Cyclic Peptides

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    Cyclic peptide compounds are a class of cyclic compounds with special structure, widely biological activity and unique mechanism of action, which play an important role in natural products. Cyclic peptides are compounds of stable and uniform conforma...

  • Post-translational Modification

    Post-translational Modification

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    Post-translational modifications (PTMs) are changes to proteins or peptides that are catalyzed by enzymes after completion of ribosomal translation and it generally have a positive impact on peptide activity. PTMs play an important role in virtually ...

  • Peptide PEGylation

    Peptide PEGylation

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    It has long been a dream in medicine and pharmacy to use peptides and proteins as drugs. The driving force for this interest is the ability of these compounds to eliminate toxic or overproduced compounds in the body and to mimic endogenous hormones, ...

  • Amino Acids Modification

    Amino Acids Modification

    Biological Sciences Shirley (New York) July 18, 2019 Check with publisher

    Chemical modifications of peptides introduced strategically at potential enzymatic cleavage sites may dramatically increase the in vivo stability of peptide drug candidates. One simple approach to stabilizing a peptide is to modify the side-chains of...