Biomedical Sciences

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  • DrugAge database of compounds that increase lifespan

    DrugAge database of compounds that increase lifespan

    Biomedical Sciences Liverpool August 24, 2015 Check with publisher

    We're starting a new database of drugs and compounds (including natural products) with anti-ageing properties that extend longevity in model organisms. The database will be called DrugAge, and although we have some data already, we are looking for da...

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  • Hit to Lead

    Hit to Lead

    Biomedical Sciences Shirley (New York) November 28, 2019 Check with publisher

    Creative Biolabs provides hit to lead service to help you determine various physical, biological and chemical characters of the hits. Our medicinal chemists deliver the most high-quality lead series to our clients within agreed timelines across a bro...

  • Yeast Expression System

    Yeast Expression System

    Biomedical Sciences Shirley (New York) October 30, 2019 Check with publisher

    Yeast expression system is a common alternative antibody expression system to E. coli. It generally achieves the highest expression level in eukaryotic system including both secretion and intracellular expression. Yeast cells both have the advantages...

  • Interference with Fungal Cell Membrane

    Interference with Fungal Cell Membrane

    Biomedical Sciences Shirley (New York) October 30, 2019 Check with publisher

    The emerging technology of whole-genome sequencing enables exploration of therapeutic targets against pathogenic fungi to a previously unprecedented extent. However, no matter in the past or present, fungal cell membrane has always been a predominant...

  • Antifungal Synergistic and Antagonistic Effects Testing

    Antifungal Synergistic and Antagonistic Effects Testing

    Biomedical Sciences Shirley (New York) October 30, 2019 Check with publisher

    Novel drugs and/or new approaches to combat infective fungi and overcome fungal resistance are urgently needed. Pay attention to the interactions between different drugs is an economical method. Creative Biolabs provides in vitro assays to measure th...

  • Parallel Artificial Membrane Permeability Assay (PAMPA)

    Parallel Artificial Membrane Permeability Assay (PAMPA)

    Biomedical Sciences Shirley (New York) October 30, 2019 Check with publisher

    Passive diffusion is an important way for drug absorption. It influences drugs pass through the intestinal epithelium, the blood brain barrier or transport across cell membranes. The PAMPA model is an artificial in vitro model suitable for the passiv...

  • Yeast Expression System

    Yeast Expression System

    Biomedical Sciences Shirley (New York) October 30, 2019 Check with publisher

    Yeast expression system is a common alternative antibody expression system to E. coli. It generally achieves the highest expression level in eukaryotic system including both secretion and intracellular expression. Yeast cells both have the advantages...

  • Apoptosis and Programmed Cell Death Assessment

    Apoptosis and Programmed Cell Death Assessment

    Biomedical Sciences Shirley (New York) October 30, 2019 Check with publisher

    Apoptosis is a type of programmed cell death (PCD), which is defined as a highly regulated process of cell elimination. Key events of apoptotic cells involve cell shrinking, nuclear and chromosomal fragmentation, PARP cleavage, etc. Two major pathway...

  • Fc Profiling Services

    Fc Profiling Services

    Biomedical Sciences Shirley (New York) October 30, 2019 Check with publisher

    Antibody fragment crystallizable (Fc) region plays a critical part in eliciting indirect target elimination including ADCC, ADCP, CDC, all of which compose vital functioning mechanisms of most therapeutic antibodies. Over the past decade, Fc region i...

  • Endocytosis and Internalization Potency Detection

    Endocytosis and Internalization Potency Detection

    Biomedical Sciences Shirley (New York) October 30, 2019 Check with publisher

    One important mechanism of action of therapeutic antibodies is to induce internalization and turnover of cell surface receptors, resulting in receptor down-modulation as well as antibody endocytosis. This receptor-mediated internalization exhibits gr...

  • Bacterial Cell Wall Targets Identification

    Bacterial Cell Wall Targets Identification

    Biomedical Sciences Shirley (New York) October 30, 2019 Check with publisher

    Bacterial cell walls potentially fulfill the principle of an ideal antibacterial drug target. Firstly, the disruption of bacterial cell walls is vital to bacteria living for maintaining osmotic pressure and protecting the cellular contents from the e...

  • Interference with Nucleic Acid Synthesis

    Interference with Nucleic Acid Synthesis

    Biomedical Sciences Shirley (New York) October 30, 2019 Check with publisher

    Gene is the manipulator of life. It consists of a large number of nucleic acids and is responsible for the direction of metabolism throughout the life of a cell. They direct the synthesis of protein, control the production of enzymes, and are respons...

  • Magic™ Humanized Immune Checkpoint Mice

    Magic™ Humanized Immune Checkpoint Mice

    Biomedical Sciences Shirley (New York) October 30, 2019 Check with publisher

    As a leading innovator as well as a long-term dedicated service provider, Creative Biolabs has successfully launched, commercialized and optimized an exclusive Magic™ therapeutic antibody discovery platform using a variety of state-of-the-art technol...