Biological Sciences

Listings
  • Investigative or Screening Studies

    Investigative or Screening Studies

    Biological Sciences Shirley (New York) November 28, 2019 Check with publisher

    Creative Biolabs now offers a comprehensive range of in vivo pharmacokinetic (PK) investigative studies and screening studies that includes quick turnaround PK screening for lead optimization or formulation evaluation, which could be conducted in rod...

  • Fear Conditioning Test

    Fear Conditioning Test

    Biological Sciences Shirley (New York) November 28, 2019 Check with publisher

    In a conditioning context, administration of a footshock (US) is paired with a tone (CS) in a certain test situation. Animals are placed in a box enclosure and receive multiple exposures of CS-US pairing (usually 1-5 times). Following an interval tha...

  • Pharmacokinetic Assays

    Pharmacokinetic Assays

    Biological Sciences Shirley (New York) November 28, 2019 Check with publisher

    Pharmacokinetics (PK) studies are of great importance in creating new therapeutic drugs, understanding both the beneficial and harmful effects of drugs, and guiding drug development experiments and trials. In PK assays, the applied assay method shoul...

  • Cassette Dosing Studies

    Cassette Dosing Studies

    Biological Sciences Shirley (New York) November 28, 2019 Check with publisher

    Cassette dosing is an efficient technique mainly applied in drug discovery efforts of pre-clinical studies, in order to obtain pharmacokinetic data from multiple candidate drugs in a single experiment. Thus, a similar amount of information obtained f...

  • PK Biomarker Assessment

    PK Biomarker Assessment

    Biological Sciences Shirley (New York) November 28, 2019 Check with publisher

    The importance of biomarkers in drug discovery is now constantly increasing. In in vivo pharmacokinetic studies of drug development, a biomarker can be used to monitor disease progress, confirm mechanism of action, and also be used as a surrogate for...

  • Mass Balance Studies

    Mass Balance Studies

    Biological Sciences Shirley (New York) November 28, 2019 Check with publisher

    As an experienced Contract Research Organization (CRO), Creative Biolabs is committed to providing services of in vivo PK studies for the global pharmaceutical and biotech industries. Based on advanced technology and professional scientists, now we c...

  • Magic™ Fluorogen Activating Protein (FAP) Assay for Internalization Assessment

    Magic™ Fluorogen Activating Protein (FAP) Assay for Internalization Assessment

    Biological Sciences Shirley (New York) November 28, 2019 Check with publisher

    Receptor-mediated endocytosis is an endocytotic process in which specific molecules are taken into the cell when binding to surface receptors. It is highly receptor-specific, and not all surface receptors are capable of triggering ligand internalizat...

  • Magic™ Humanized PD-1/LAG-3 Dual Immune Checkpoint Knock-In Mice

    Magic™ Humanized PD-1/LAG-3 Dual Immune Checkpoint Knock-In Mice

    Biological Sciences Shirley (New York) November 28, 2019 Check with publisher

    More and more evidence suggests that elevated expression of inhibitory receptors on tumor antigen-specific T cells is one of the mechanisms by which tumors evade host immune surveillance. Blockade of certain individual inhibitory receptor with specif...

  • Sleeping Beauty Transposon System

    Sleeping Beauty Transposon System

    Biological Sciences Shirley (New York) November 28, 2019 Check with publisher

    Sleeping Beauty (SB) transposon is a synthetic transposon of the Tc1-like mariner family. It was originally discovered in salmon, where it had been silenced through evolution and was then reconstructed by investigators based on molecular phylogenetic...

  • Tol2 Transposon System

    Tol2 Transposon System

    Biological Sciences Shirley (New York) November 28, 2019 Check with publisher

    The Tol2 transposon element was originally identified in the genome of the medaka fish and has now been extensively used to make transgenic zebrafish model for various studies. Afterward, this Tol2 transposon was discovered to be active in many other...

  • PiggyBac Transposon System

    PiggyBac Transposon System

    Biological Sciences Shirley (New York) November 28, 2019 Check with publisher

    The PiggyBac transposon superfamily is relatively recently recognized as a widespread DNA transposon family with a broad host spectrum from yeast to mammals. This type of transposon was originally thought to be a rare transposon but now it has been d...

  • In Vitro Display

    In Vitro Display

    Biological Sciences Shirley (New York) November 28, 2019 Check with publisher

    Phage display is one of the most powerful and widely used in vitro display techniques for the study of protein-protein, protein-peptide, and protein-DNA interactions. Target gene encoding the interest protein is inserted into bacteriophage coat prote...