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  • Characterization and functional analysis of a novel cancer-associated gene

    Characterization and functional analysis of a novel cancer-associated gene

    PhD Studentships Liverpool May 15, 2016 Check with publisher

    Genes involved in common biological processes and diseases tend to be co-expressed. Therefore, genes co-expressed with known disease-associated genes will help identify new candidates for further studies. Our lab has recently developed a co-expressio...

  • DrugAge database of compounds that increase lifespan

    DrugAge database of compounds that increase lifespan

    Biomedical Sciences Liverpool August 24, 2015 Check with publisher

    We're starting a new database of drugs and compounds (including natural products) with anti-ageing properties that extend longevity in model organisms. The database will be called DrugAge, and although we have some data already, we are looking for da...

  • Expertise in genomics and transcriptomics

    Expertise in genomics and transcriptomics

    Data Analysis - Analytics August 24, 2015 Check with publisher

    I lead the Integrative Genomics of Ageing Group (http://pcwww.liv.ac.uk/~aging/), and I have extensive experience in data analysis and integration of multidimensional data. Although my lab’s research integrates different strategies, its focal point i...

Listings
  • Recombinant Human CD4 Protein(His tag)

    Recombinant Human CD4 Protein(His tag)

    Medical Sciences Shirley (New York) May 30, 2019 Check with publisher

    Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts. (Microbial infection) Acts as a receptor for human immunodeficiency virus-1 (PubMed:2214026, PubMed:163319...

  • Recombinant Human LDLR Protein(His tag)

    Recombinant Human LDLR Protein(His tag)

    Immunology Shirley (New York) May 30, 2019 10.00 Dollar US$

    Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. (Microbial infection) Acts as a rec...

  • Recombinant Mouse Lag3 Protein(His tag)

    Recombinant Mouse Lag3 Protein(His tag)

    Molecular Biology Shirley (New York) May 30, 2019 10.00 Dollar US$

    Involved in lymphocyte activation. Binds to HLA class-II antigens (By similarity). Recombinant Mouse Lag3 Protein (Q61790) (Gly 24 - Leu 442) with a polyhistidine tag at the C-terminus was expressed in HEK293. https://www.profacgen.com/rmouse-lag3-hi...

  • Recombinant Human LAG3 Protein(His tag)

    Recombinant Human LAG3 Protein(His tag)

    Data Management Shirley (New York) May 30, 2019 10.00 Dollar US$

    Involved in lymphocyte activation. Binds to HLA class-II antigens. Recombinant Human LAG3 Protein (P18627) (Leu 23 - Leu 450) with a polyhistidine tag at the C-terminus was expressed in HEK293. https://www.profacgen.com/rhuman-lag3-his-tag-1337.htm

  • Recombinant Human IL7R Protein(Fc tag)

    Recombinant Human IL7R Protein(Fc tag)

    Drug Development Shirley (New York) May 30, 2019 10.00 Dollar US$

    Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP). Recombinant Human IL7R Protein (P16871) (Glu 21 - Gly 236) with a human IgG1 Fc tag at the C-terminus was expressed in HEK293. https://www.profacgen.com/rhum...

  • Recombinant Human IL33 Protein

    Recombinant Human IL33 Protein

    Life Sciences Shirley (New York) May 30, 2019 Check with publisher

    Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells (PubMed:16286016). Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-ass...

  • Recombinant Human FGFR1 Protein(His tag)

    Recombinant Human FGFR1 Protein(His tag)

    Cell Biology & Microbiology Shirley (New York) May 30, 2019 10.00 Dollar US$

    Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patternin...

  • Recombinant Mouse Egfr Protein(His tag)

    Recombinant Mouse Egfr Protein(His tag)

    Molecular Biology Shirley (New York) May 30, 2019 10.00 Dollar US$

    Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacell...

  • Recombinant Human EGFR Protein(Avi&His tag), Biotinylated

    Recombinant Human EGFR Protein(Avi&His tag), Biotinylated

    Molecular Biology Shirley (New York) May 30, 2019 10.00 Dollar US$

    Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacell...

  • Recombinant Human CD226 Protein(Fc tag)

    Recombinant Human CD226 Protein(Fc tag)

    Pharmacology - Drug Development Shirley (New York) May 30, 2019 Check with publisher

    Receptor involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell. Recombinant Human CD226 Protein (Q15762) (Glu 19 - Asn 247) with a human IgG1 Fc tag at the...

  • Recombinant Human CTLA4 Protein(Fc tag)

    Recombinant Human CTLA4 Protein(Fc tag)

    Life Sciences Shirley (New York) May 30, 2019 Check with publisher

    Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. Recombinant...

  • Recombinant Human CD38 Protein(Fc tag)

    Recombinant Human CD38 Protein(Fc tag)

    Biomedical Sciences Shirley (New York) May 30, 2019 Check with publisher

    Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the im...