Project Offers - Collaborations
Premium listings
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DrugAge database of compounds that increase lifespan
Biomedical Sciences Liverpool August 24, 2015 Check with publisherWe're starting a new database of drugs and compounds (including natural products) with anti-ageing properties that extend longevity in model organisms. The database will be called DrugAge, and although we have some data already, we are looking for da...
Listings
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Nitrosation
Biomedical Sciences Shirley (New York) March 11, 2019 Check with publisherNitrosation is the reaction introducing nitroso (-NO) to the carbon or nitrogen atoms of organic molecules. The commonly used reagents for nitrosation are nitrous acid (nitrite plus acid) and nitrite. Compared with nitro compounds, nitroso groups pos...
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Diazotization
Biomedical Sciences Shirley (New York) March 11, 2019 Check with publisherDiazotization is the reaction of primary amine and nitrite at low temperature to produce diazonium salt. The reaction of aromatic amine and nitrite to produce diazonium is diazotized. Aromatic amine is often used as a heavy nitrogen component and nit...
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Azidation
Biomedical Sciences Shirley (New York) March 11, 2019 Check with publisherOrganic azide compounds contain azide-based high-energy reactive functional groups and are an important class of organic synthesis intermediates and target compounds, which are widely used in organic synthesis, chemical biology, functional materials,...
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Process R&D
Biomedical Sciences Shirley (New York) March 11, 2019 Check with publisherAbout 30 years ago, “Process R&D” in the pharmaceutical market only refers to make a chemical process scalable. With the growing awareness of the need to change and develop more efficient processes in pharma industry, a new chemistry filed “Proce...
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Route Scouting and Development
Biomedical Sciences Shirley (New York) March 11, 2019 Check with publisherRoute scouting refers to discussion and investigation of completely different routes to the target molecules. Recently, route scouting for preclinical and clinical development has emerged as an important area of interest. The impact of good route sel...
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Reaction Condition Optimization
Biomedical Sciences Shirley (New York) March 11, 2019 Check with publisherAs new drugs continue to be marketed, strategies to improve drug development and manufacturing processes become critical. In the development of pharmaceutical and chemical products, it is becoming more and more important to improve the yield, reduce ...
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Scale-up
Biomedical Sciences Shirley (New York) March 11, 2019 Check with publisher"Scaling-up" refers to increasing the scale of a product, device, process or technology that operate at a smaller scale. Much time has been spent, large scale production plant has been established based on laboratory data, however, it turns out that ...
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technology transfer
Biomedical Sciences Shirley (New York) March 11, 2019 Check with publisherIn the past, technology transfer (tech transfer) mainly referred to standard transfer or technology instruction from technology department to production department within the same company. Now tech transfer is the process by which an original innovat...
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Analysis/Purification
Biomedical Sciences Shirley (New York) March 11, 2019 Check with publisherImpurities and the unwanted by-products, especially the potentially toxic compounds, should be strictly controlled below a certain level set by the regulatory agencies. That’s mainly ascribed to the fact that these pharmaceutical impurities such as r...
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Problems with Aging Physicians
Clinical/Medical Sciences Fremont (California) March 20, 2019 Check with publisherOverview: Practicing medicine is not like other jobs that have a tradition of retirement at age 65. Physician shortages fuel support for physicians seeking to continue their careers indefinitely. Patient safety is paramount, but is it served by apply...
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Physician Employment Agreements: Items to Consider
Clinical/Medical Sciences Fremont (California) March 20, 2019 Check with publisherOverview: We will review the various elements of the physician employment agreement, focusing on the pitfalls and the problems that can develop when the agreement does not clearly define the relationship, and/or when the parties do not fully understa...
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Federal Requirements for Interoperability - New Directions for EHRs, Patient and Provider Data
Clinical/Medical Sciences Fremont (California) March 20, 2019 Check with publisherOverview: In March 2019, the Department of Health and Human Services issued proposed rules to give providers and patients access to the electronic data stored in EHRs and health plans. These rules require specific technology (APIs using the HL7 Fast ...
