Biomedical Sciences

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  • DrugAge database of compounds that increase lifespan

    DrugAge database of compounds that increase lifespan

    Biomedical Sciences Liverpool August 24, 2015 Check with publisher

    We're starting a new database of drugs and compounds (including natural products) with anti-ageing properties that extend longevity in model organisms. The database will be called DrugAge, and although we have some data already, we are looking for da...

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  • Molecular Engineering

    Molecular Engineering

    Biomedical Sciences Shirley (New York) January 15, 2020 Check with publisher

    Structure-based drug design is the design and optimization of a hit's structure to make it more suitable for becoming a drug candidate. The structure-based design is based on a thoroughly understanding of various characters of a hit, which means how ...

  • Magic™ Humanized PD-1/PD-L1 Dual Immune Checkpoint Knock-In Mice

    Magic™ Humanized PD-1/PD-L1 Dual Immune Checkpoint Knock-In Mice

    Biomedical Sciences Shirley (New York) February 11, 2020 Check with publisher

    The therapy of using monoclonal antibodies against inhibitory receptors on immune cells, termed immune-checkpoint blockade, for the treatment of human cancer has gained a great deal of attention among clinicians, scientists, and patients. Checkpoint ...

  • Antibody Expression

    Antibody Expression

    Biomedical Sciences Shirley (New York) January 15, 2020 Check with publisher

    Recombinant antibodies are widely used in research, diagnostics and therapeutic areas. Antibody generation has been dramatically accelerated by in vitro selection systems, particularly phage display. These new antibody generation technologies have in...

  • Magic™ Humanized IL-6R Immune Checkpoint Knock-In Mice

    Magic™ Humanized IL-6R Immune Checkpoint Knock-In Mice

    Biomedical Sciences Shirley (New York) February 11, 2020 Check with publisher

    Soluble cytokine receptors play pivotal roles in health and disease. Signaling of the IL-6 (cytokine interleukin-6) via its ligand, sIL-6R (soluble IL-6 receptor) is causative for the proinflammatory properties of IL-6 and appears to be an attractive...

  • Structure-Based Drug Design

    Structure-Based Drug Design

    Biomedical Sciences Shirley (New York) January 15, 2020 Check with publisher

    Creative Biolabs provides one-step service for structure-based drug design. Our short outline of this process includes: Primarily, choose a target and evaluate the structure information. Secondary, screening different compound libraries, including ta...

  • Magic™ Humanized PD-1/PD-L1 Dual Immune Checkpoint Knock-In Mice

    Magic™ Humanized PD-1/PD-L1 Dual Immune Checkpoint Knock-In Mice

    Biomedical Sciences Shirley (New York) February 11, 2020 Check with publisher

    The therapy of using monoclonal antibodies against inhibitory receptors on immune cells, termed immune-checkpoint blockade, for the treatment of human cancer has gained a great deal of attention among clinicians, scientists, and patients. Checkpoint ...

  • Chemical Synthesis

    Chemical Synthesis

    Biomedical Sciences Shirley (New York) January 15, 2020 Check with publisher

    Creative Biolabs offers chemical synthesis service to synthesize therapeutic compounds. Our company is able to synthesize nearly all compounds you required. We are able to offer a broad range of materials used in this process, including intermediates...

  • Magic™ Humanized ICOS Immune Checkpoint Knock-In Mice

    Magic™ Humanized ICOS Immune Checkpoint Knock-In Mice

    Biomedical Sciences Shirley (New York) February 11, 2020 Check with publisher

    ICOS (Inducible T-cell co-stimulator), also known as CD278, is a CD28-superfamily costimulatory molecule that is expressed on activated T cells as well as regulatory T cells. It is encoded by the ICOS gene. ICOS forms homodimers and plays a critical ...

  • Antimicrobial Pharmacodynamics

    Antimicrobial Pharmacodynamics

    Biomedical Sciences Shirley (New York) January 15, 2020 Check with publisher

    Creative Biolabs provides both broth-based and agar-based assays for evaluating MIC. For broth-based assays, broth macrodilution and broth microdilution are provided. For agar-based assays, disk diffusion, Etest, and colorimetric assays are provided....

  • Magic™ Humanized VEGI Immune Checkpoint Knock-In Mice

    Magic™ Humanized VEGI Immune Checkpoint Knock-In Mice

    Biomedical Sciences Shirley (New York) February 11, 2020 Check with publisher

    Vascular endothelial growth inhibitor (VEGI), also known as TNF-like ligand 1A (TL1A) and TNF superfamily member 15 (TNFSF15), is an anti-angiogenic protein which is coded by the TNFSF15 gene. It has a carboxyl-terminal which is present on the exteri...

  • Dose-Response Relationship

    Dose-Response Relationship

    Biomedical Sciences Shirley (New York) January 15, 2020 Check with publisher

    Studying dose response, and developing dose-response models, is vitally important for determining dosages for drugs. The dose-response relationship describes the change in effect on an organism caused by differing levels of drug doses after a certain...

  • Magic™ GPCR Stable Cell Lines For Antibody Function Study

    Magic™ GPCR Stable Cell Lines For Antibody Function Study

    Biomedical Sciences Shirley (New York) February 11, 2020 Check with publisher

    G protein-coupled receptors (GPCRs) belong to a superfamily of cell surface signaling proteins that have a pivotal role in many physiological functions and in multiple diseases, including the development of cancer and cancer metastasis. Drugs especia...