Project Offers - Collaborations

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  • DrugAge database of compounds that increase lifespan

    DrugAge database of compounds that increase lifespan

    Biomedical Sciences Liverpool August 24, 2015 Check with publisher

    We're starting a new database of drugs and compounds (including natural products) with anti-ageing properties that extend longevity in model organisms. The database will be called DrugAge, and although we have some data already, we are looking for da...

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  • PK Biomarker Assessment

    PK Biomarker Assessment

    Biological Sciences Shirley (New York) November 28, 2019 Check with publisher

    The importance of biomarkers in drug discovery is now constantly increasing. In in vivo pharmacokinetic studies of drug development, a biomarker can be used to monitor disease progress, confirm mechanism of action, and also be used as a surrogate for...

  • Mass Balance Studies

    Mass Balance Studies

    Biological Sciences Shirley (New York) November 28, 2019 Check with publisher

    As an experienced Contract Research Organization (CRO), Creative Biolabs is committed to providing services of in vivo PK studies for the global pharmaceutical and biotech industries. Based on advanced technology and professional scientists, now we c...

  • Magic™ Fluorogen Activating Protein (FAP) Assay for Internalization Assessment

    Magic™ Fluorogen Activating Protein (FAP) Assay for Internalization Assessment

    Biological Sciences Shirley (New York) November 28, 2019 Check with publisher

    Receptor-mediated endocytosis is an endocytotic process in which specific molecules are taken into the cell when binding to surface receptors. It is highly receptor-specific, and not all surface receptors are capable of triggering ligand internalizat...

  • Magic™ Humanized PD-1/LAG-3 Dual Immune Checkpoint Knock-In Mice

    Magic™ Humanized PD-1/LAG-3 Dual Immune Checkpoint Knock-In Mice

    Biological Sciences Shirley (New York) November 28, 2019 Check with publisher

    More and more evidence suggests that elevated expression of inhibitory receptors on tumor antigen-specific T cells is one of the mechanisms by which tumors evade host immune surveillance. Blockade of certain individual inhibitory receptor with specif...

  • Sleeping Beauty Transposon System

    Sleeping Beauty Transposon System

    Biological Sciences Shirley (New York) November 28, 2019 Check with publisher

    Sleeping Beauty (SB) transposon is a synthetic transposon of the Tc1-like mariner family. It was originally discovered in salmon, where it had been silenced through evolution and was then reconstructed by investigators based on molecular phylogenetic...

  • Tol2 Transposon System

    Tol2 Transposon System

    Biological Sciences Shirley (New York) November 28, 2019 Check with publisher

    The Tol2 transposon element was originally identified in the genome of the medaka fish and has now been extensively used to make transgenic zebrafish model for various studies. Afterward, this Tol2 transposon was discovered to be active in many other...

  • PiggyBac Transposon System

    PiggyBac Transposon System

    Biological Sciences Shirley (New York) November 28, 2019 Check with publisher

    The PiggyBac transposon superfamily is relatively recently recognized as a widespread DNA transposon family with a broad host spectrum from yeast to mammals. This type of transposon was originally thought to be a rare transposon but now it has been d...

  • In Vitro Display

    In Vitro Display

    Biological Sciences Shirley (New York) November 28, 2019 Check with publisher

    Phage display is one of the most powerful and widely used in vitro display techniques for the study of protein-protein, protein-peptide, and protein-DNA interactions. Target gene encoding the interest protein is inserted into bacteriophage coat prote...

  • Humanized CD34 NSG Mice

    Humanized CD34 NSG Mice

    Biological Sciences Shirley (New York) November 28, 2019 Check with publisher

    Human CD34+ hematopoietic stem cell-engrafted NSG mice, which have developed multi-lineage human immune cells, are a supreme in vivo platform for long-term study on hematopoiesis, infectious disease, immuno-oncology and graft-versus-host disease. Cre...

  • In Vivo Fitness Assessment of Drug Candidates

    In Vivo Fitness Assessment of Drug Candidates

    Biological Sciences Shirley (New York) November 28, 2019 Check with publisher

    Unspecific binding of drug candidates to other proteins is investigated in vitro using the protein microarray technique developed by our developability assessment groups. The objective of this assay is to provide a multitude of protein epitopes for t...

  • In Vivo ADME

    In Vivo ADME

    Biological Sciences Shirley (New York) November 28, 2019 Check with publisher

    Preclinical in vivo ADME study is an important component of the drug development process which is designed to investigate the absorption, distribution, metabolism, and excretion of test articles. In addition to supporting drug discovery, lead candida...

  • In Vivo PK Studies

    In Vivo PK Studies

    Biological Sciences Shirley (New York) November 28, 2019 Check with publisher

    As a reliable partner of the top global pharma companies and research agencies, Creative Biolabs brings together the market-leading in vivo PK (pharmacokinetic) expertise to build our in vivo PK service team. We are recognized as the world leader for...