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  • Published date: December 24, 2019
    • Shirley, New York, United States

Azacitidine is a potent growth inhibitor and a cytotoxic agent. It acts as a demethylating agent by inhibiting DNA methyltransferase (Dnmt), forming covalent adducts with cellular DNMT1 depleting enzyme activity. It also improves the efficiency of reprogramming of stem cells and induces differentiation of mesenchymal stem cells into cardiomyocytes.

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Alex Brown
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