CD70 h(41BB-CD3ζ) CAR, [T]

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  • Published date: December 26, 2019
    • Shirley, New York, United States

The vector of anti-CD70 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human CD70. The T cells are genetically modified through transduction with a lentiviral vector expressing the full-length CD70 receptor (CD27) linked to CD3-zeta and CD137 (4-1BB) signaling domains. And the vector product was designed for chronic lymphocytic leukemia (CLL).https://www.creative-biolabs.com/car-t/pcdcar1-cd70-h-bb%CE%B6-t-798.htm

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Jerry Carter
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