G250 h(CD4-CD3ζ) CAR, [T]

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  • Published date: December 26, 2019
    • Shirley, New York, United States

The vector of anti-G250 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human G250. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-G250 antibody linked to a CD4 transmembrane domain and CD3-zeta signaling domains. And the vector product was designed for modifying T lymphocytes, and the modified T lymphocytes was designed for renal carcinoma treatment.https://www.creative-biolabs.com/car-t/pcdcar1-g250-h-4%CE%B6-t-793.htm

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Jerry Carter
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