κ light chain h(CD28) CAR, [T]

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  • Published date: December 26, 2019
    • Shirley, New York, United States

The vector of anti-κ light chain chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human κ light chain. The T cell is genetically modified through transduction with a lentiviral vector expressing scFv of anti-κ light chain antibody linked to CD28 signaling domains. And the vector product was designed for the treatment of B cell-chronic lymphocytic leukemia (B-CLL).https://www.creative-biolabs.com/car-t/pcdcar1-ig-%CE%BA-light-chain-h-28-t-776.htm

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Jerry Carter
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