Mannosylated Fluorescent Liposome DiA

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  • Published date: December 30, 2020
    • United States

Mannose receptor targeting by mannosylated liposomes has been demonstrated for a variety of mannosylated lipid conjugates in a variety of liposome morphologies and compositions in several different models. Mannosylated Fluorescent Liposome DiA incorporates a lipophilic dye inside its membrane, which is insoluble in water. Its fluorescence is easily detected when incorporated into membranes. The emission spectrum of DiA is very broad, allowing it to be detected as green, orange or even red fluorescence depending on the optical filter used. It has extremely high extinction coefficients, moderate fluorescence quantum yields and short excited state lifetimes in lipid environments (~1 ns).
https://www.creative-biolabs.com/lipid-based-delivery/mannosylated-fluorescent-liposome-dia-10.htm

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Jerry Carter
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