STEMOD™ CPVT1 Disease Model (RYR2, p.F2483I (c.7447T>A))

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  • Published date: January 26, 2021
    • United States

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited life-threatening arrhythmia leading to syncope and sudden cardiac death at a young age. This disease cell model belongs to CPVT1, an autosomal dominant mutations (p.F2483I, also called c.7447T>A) occur in the RYR2 gene. Generating pluripotent stem cells from dermal fibroblasts, then differentiate into cardiac myocytes. This disease cell model provides a platform to explore disease mechanisms in human genetic cardiac disorders.https://www.creative-biolabs.com/stem-cell-therapy/cpvt1-disease-model-ryr2-p-f2483i-c-7447t-a-41.htm

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Jerry Carter
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