STEMOD™ CPVT2 Disease Model (CASQ2, D307H (c.1183G>C))

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  • Published date: January 26, 2021
    • United States

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited life-threatening arrhythmia leading to syncope and sudden cardiac death at a young age. This disease cell model belongs to CPVT2, an autosomal recessive mutations (D307H, also called c.1183G>C) occur in the CASQ2 gene. Generating pluripotent stem cells from skin fibroblasts, then differentiate into cardiac myocytes. This disease cell model provides a platform to explore disease mechanisms in human genetic cardiac disorders.https://www.creative-biolabs.com/stem-cell-therapy/cpvt2-disease-model-casq2-d307h-c-1183g-c-43.htm

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