Anti-CD22 scFv h(CD28-CD3ζ) CART, pCDCAR1

  • 1.00 Dollar US$
  • Published date: February 8, 2018
    • Shirley, New York, United States

https://www.creative-biolabs.com/car-t/pcdcar1-cd22-h-28ζ-t-101.htm The vector of anti-CD22 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human CD22. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-CD22 antibody linked to CD28 transmembrane domain/ endodomain and CD3-zeta signaling domains. And the vector product was designed for the treatment of acute lymphoblastic leukemia (ALL) .

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