Anti-ErbB2 scFv h(CD4-CD3ζ) CARNK, pCDCAR1

  • 1.00 Dollar US$
  • Published date: March 6, 2018
    • Shirley, New York, United States

https://www.creative-biolabs.com/car-t/pcdcar1-erbb2-h-4ζ-nk-282.htm The vector of anti-ErbB2 (HER2) chimeric antigen receptor(CAR) is constructed for the engineering of NK cell to target human ErbB2. The NK cell is genetically modified through transduction with a lentiviral vector expressing scFv of anti-ErbB2 antibody linked to CD4 transmembrane domain and CD3-zeta signaling domains. And the vector product was designed for the treatment of breast carcinomas, ovarian carcinoma .

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