Anti-FOLR1-DGN462 ADC

  • 1.00 Dollar US$
  • Published date: December 15, 2017
    • Shirley, New York, United States

https://www.creative-biolabs.com/adc/target-folh1-46.htm This ADC product is comprised of an anti-FOLR1 monoclonal antibody conjugated via a linker to DGN462. The DGN462 is targeted to certain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. DGN462,the mono-imine IGN, highly potent cytotoxic DNA alkylateing agent.DGN462 formed covalent DNA adducts through alkylation of the C2-amino group of guanine.

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