Anti-MUC1 scFv h(CD28-41BB-CD3ζ) CART, pCDCAR1

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  • Published date: March 6, 2018
    • Shirley, New York, United States

https://www.creative-biolabs.com/car-t/pcdcar1-muc1-h-28bbζ-t-453.htm The vector of anti-MUC1 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human MUC1. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-MUC1 antibody linked to CD28 transmembrane domain/ endodomain and CD137 (4-1BB), CD3-zeta signaling domains. And the vector product was designed for the treatment of MUC1-expressing tumors . pCDCAR1 MUC1 h(28BBζ), T

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Jerry Carter
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