Bulk Antibody Production

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  • Published date: June 14, 2016
  • Modified date: June 27, 2017
    • Bedford, United Kingdom

APS is an independently owned UK based company providing contract services to meet the growing demand of outsourcing production. Our bulk antibody production service offers a fully managed service providing a customisable and adaptable approach to the large scale production of antibodies.
* Adaptation of both hybridoma and transfected mammalian cell lines to regulatory compliant protein free media.
* Scale-up in roller bottle culture to 150 litre. Roller bottles allow scaled process development such that parameters developed for small scale are directly transposed into larger scale.
* Tangential cross flow concentration of crude feedstock and subsequent downstream purification using either protein A/G or affinity chromatography.
* Bespoke formulation with associated QC: SDSPAGE, Western blot, quantitative assay.
* Preparation and storage of working cell banks for subsequent lot production.
* All work carried out in UK laboratories to ISO:9001 quality standard.

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Anne van der Valk
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