Internalizing Antibody Screening Service

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  • Published date: April 20, 2017
    • United States

Creative BioLabs offers high-throughput phage display library screening services for selection of receptor-dependent antibodies and peptides that can be internalized into mammalian cells. Internalizing antibodies and peptides specific for cell surface receptors, which upon binding will induce receptor-mediated endocytosis, are highly suitable vehicles for targeted delivery of drugs, toxins, enzymes or DNA into the cytosol of mammalian cells for therapeutic applications. Compared with receptor-independent antibodies and peptides that can penetrate cell membrane without binding to a receptor, receptor-mediated internalizing antibodies and peptides confer cell-specific drug delivery, the fundamental requirement for targeted therapy. Selection of receptor-mediated internalizing antibodies and peptides from phage display library can also be employed to identify cell-specific markers, the endocytosed receptors that are associated with a specific cellular function.More information, please visit the website: http://www.creative-biolabs.com/Screening-for-Internalizing-Antibodies-and-Peptides.html http://www.creative-biolabs.com/Screening-for-Internalizing-Antibodies-and-Peptides.html

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