SuperTM Intrabody Production

  • Check with publisher
  • Published date: April 20, 2017
  • Modified date: July 13, 2017
    • United States

Creative BioLabs has built up a novel intrabody generation platform, SuperTM Intrabody Platform, that is based on an innovative combination of Yeast Two-Hybrid System with antibody library technology.

Intrabodies are antibodies that work within cells to bind to intracellular antigens. They are directed against intracellular target molecules and expressed within a specific subcellular compartment as directed by the intracellular localization signals genetically fused to N- or C-terminus. For this reason, intrabodies are defined as antibodies that have been modified for intracellular localization. Because antibodies ordinarily are designed to be secreted from cells, intrabodies require special alterations, including modification of sequences for hyperstability,selection of antibodies resistant to the more reducing intracellular environment, or expression as a fusion protein with maltose binding protein or other stable intracellular proteins. Intrabodies have wide applications in dissecting target protein function, in target validation and functional genomics, as well as acting as potential therapeutic reagents. Intrabodies have promising applications against hepatitis B, avian influenza, prion diseases,inflammation, Parkinson's disease, and Huntington's disease. More information, please visit the website: http://www.creative-biolabs.com/Super-TM-Intrabody-Generation.html

Result 0 votes
Bella Smith
0 votes

Useful information

  • Avoid scams by acting locally or paying with PayPal
  • Never pay with Western Union, Moneygram or other anonymous payment services
  • Don't buy or sell outside of your country. Don't accept cashier cheques from outside your country
  • This site is never involved in any transaction, and does not handle payments, shipping, guarantee transactions, provide escrow services, or offer "buyer protection" or "seller certification"

Related listings

  • Mammalian Two-hybrid Service

    Mammalian Two-hybrid Service

    Immunology (United States ) April 20, 2017 Check with publisher

    Creative BioLabs offers mammalian two-hybridservice, which allows rapid and convenient analysis of protein-protein interactions in transfected mammalian cells.Compared with the yeast two-hybrid system, the mammalian two-hybrid system provides the mil...

  • Yeast Two-Hybrid Screening Service

    Yeast Two-Hybrid Screening Service

    Immunology (United States ) April 20, 2017 Check with publisher

    A key part of gene functional analysis and potential drug target discovery is an understanding of how proteins interact within the cell.The two-hybrid system is a very powerful molecular genetic tool which investigates protein-protein interactions in...

  • single domain antibody Discovery against Membrane Proteins by DNA Immunization

    single domain antibody Discovery against Membrane Proteins by DNA Immunization

    Immunology (United States ) April 20, 2017 Check with publisher

    Creative Biolabs have established a world-leading platform for single domain antibody discovery against membrane protein targets using our proprietary DNA immunization strategy. With over 10 years of experiences in providing professional antibody pha...