Human CD86 Stable Cell Line-CHO

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  • Published date: April 20, 2017
  • Modified date: April 4, 2018
    • United States

This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.
https://www.creative-biogene.com/Human-CD86-Stable-Cell-Line-CHO-1373001-15.html

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Wendy Kally
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