Human F2RL1 Stable Cell Line-CHO-K1/Gα15

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  • Published date: April 20, 2017
  • Modified date: April 5, 2018
    • United States

Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83% identical to the mouse receptor sequence.

https://www.creative-biogene.com/Human-F2RL1-Stable-Cell-Line-CHO-K1-Gα15-1352639-11.html

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Wendy Kally
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