Human TNFRSF18 Stable Cell Line-CHO

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  • Published date: April 20, 2017
  • Modified date: April 4, 2018
    • United States

This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
https://www.creative-biogene.com/Human-TNFRSF18-Stable-Cell-Line-CHO-1373002-15.html

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Wendy Kally
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