Membrane Protein Binding Screening and Profiling

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  • Published date: April 28, 2019
  • Modified date: October 17, 2019
    • Shirley, New York, United States

Profacgen provides a highly sensitive high-throughput method for the screening of drug candidates against membrane proteins. Specifically, full-length membrane proteins which are individually expressed in human cells are used as ‘baits’ for a specific molecule to be tested. Binding of membrane protein to its target is subsequently confirmed by flow cytometry (Figure 1). As the binding events are characterized in unfixed cells, where membrane protein retain their structural integrity, the subsequent result can reflect the protein-target binding in native-status cells.
https://www.profacgen.com/membrane-protein-binding-screening-and-profiling.htm

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