Reporter-encoding Oncolytic Herpes Simplex Virus 1 (ΔICP27), CMV-luciferase

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  • Published date: December 30, 2020
    • United States

This product is a luciferase encoding oncolytic herpes simplex virus, which is based on HSV-1 with ICP27 deleted. ICP27 is highly cytotoxic probably due to its secondary role of preventing the splicing of pre-mRNAs in favour of translation from the mainly unspliced hepes RNAs. Deletion of ICP27 might produce a safer and less cytotoxic system when combined with other oncolytic-rendered modifications. This product can be used in oncolytic virotherapy research and further recombinant HSV construction.
https://www.creative-biolabs.com/oncolytic-virus/reporter-encoding-oncolytic-herpes-simplex-virus-1-icp27-cmv-luciferase-5.htm

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Jerry Carter
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