Cell Biology & Microbiology

Listings
  • HA-100 Dihydrochloride

    HA-100 Dihydrochloride

    Cell Biology & Microbiology Shirley (New York) January 2, 2020 Check with publisher

    HA-100 is an inhibitor of protein kinases including PKA, PKC, and PKG. HA-100 dihydrochloride was reported to increase human fibroblast reprogramming efficiency in combination with PD0325901, CHIR99021, A83-01 and hLIF. https://www.bocsci.com/ha-100-...

  • Hh-Ag1.5

    Hh-Ag1.5

    Cell Biology & Microbiology Shirley (New York) January 2, 2020 Check with publisher

    Hh-Ag1.5 is a smoothened receptor agonist. https://www.bocsci.com/hh-ag1-5-cas-612542-14-0-item-286089.html

  • Vismodegib

    Vismodegib

    Cell Biology & Microbiology Shirley (New York) January 2, 2020 Check with publisher

    Vismodegib is a potent and specific inhibitor of hedgehog with IC50 value of 3 nM, and it also inhibits P-gp with IC50 value of 3.0 μM. https://www.bocsci.com/vismodegib-cas-879085-55-9-item-485201.html

  • Pirfenidone

    Pirfenidone

    Cell Biology & Microbiology Shirley (New York) January 2, 2020 Check with publisher

    Pirfenidone is an inhibitor of TGF-β production and TGF-β stimulated collagen production, reducing production of TNF-α and IL-1β, and also has antifibrotic and anti-inflammatory properties. https://www.bocsci.com/pirfenidone-cas-53179-13-8-item-47888...

  • BBI-503

    BBI-503

    Cell Biology & Microbiology Shirley (New York) January 2, 2020 Check with publisher

    BBI-503 is an inhibitor of cancer cell stemness kinases with potential anticancer activity. It is an orally administered investigational agent designed to inhibit cancer stem cell pathways, including Nanog, by targeting stemness kinases. https://www....

  • Cryptotanshinone

    Cryptotanshinone

    Cell Biology & Microbiology Shirley (New York) January 2, 2020 Check with publisher

    Cryptotanshinone, a natural cell-permeable diterpene quinone isolated from Salvia miltiorrhiza, inhibits acetylcholinesterase (IC50 = 4.09 μM) and reduces Aβ peptide generation so that can treat Alzheimer's disease. It also inhibits STAT3 activity (I...

  • Artesunate

    Artesunate

    Cell Biology & Microbiology Shirley (New York) January 2, 2020 Check with publisher

    Artesunate is an antimalarial agent that effectively kills the malarial parasites P. falciparum and P. vivax (IC50 = 1.3 nM). It also exhibits inhibitory effects against leukemia and colon cancer cell lines. https://www.bocsci.com/artesunate-cas-8849...

  • Fludarabine

    Fludarabine

    Cell Biology & Microbiology Shirley (New York) January 2, 2020 Check with publisher

    Fludarabine, a DNA synthesis inhibitor, is a chemotherapy drug used in the treatment of hematological malignancies. https://www.bocsci.com/fludarabine-cas-21679-14-1-item-471674.html

  • Fasudil hydrochloride

    Fasudil hydrochloride

    Cell Biology & Microbiology Shirley (New York) January 2, 2020 Check with publisher

    Fasudil is a selective ROCK inhibitor with antineoplastic activity. It was shown to suppress MMP-2 expression and induce apoptosis in glioblastoma cells. https://www.bocsci.com/fasudil-hydrochloride-cas-105628-07-7-item-471472.html

  • Curcumol

    Curcumol

    Cell Biology & Microbiology Shirley (New York) January 2, 2020 Check with publisher

    Curcumol is a pure monomer isolated from Rhizoma Curcumaeis with antitumor activity. Curcumol was shown to suppress the stemness ability of choriocarcinoma cancer stem-like cells (CSLCs) via inhibition of DNMTs and HDACs. https://www.bocsci.com/curcu...

  • (S)-Ruxolitinib

    (S)-Ruxolitinib

    Cell Biology & Microbiology Shirley (New York) January 2, 2020 Check with publisher

    (S)-Ruxolitinib is the S enantiomer of Ruxolitinib, a potent and selective inhibitor of JAK1 and JAK2. https://www.bocsci.com/s-ruxolitinib-cas-941685-37-6-item-479378.html

  • Tofacitinib Citrate

    Tofacitinib Citrate

    Cell Biology & Microbiology Shirley (New York) January 2, 2020 Check with publisher

    Tofacitinib Citrate is a JAK inhibitor developed for the treatment of rheumatoid arthritis (RA). It has been investigated for psoriasis, inflammatory bowel disease, and other immunological diseases, as well as for the prevention of organ transplant r...