Immunology
Listings
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PDX-based Drug Screening
Immunology New York (New York) October 30, 2024 1.00 Dollar US$To better preserve the genomic integrity and tumor heterogeneity observed in patients, patient-derived xenograft (PDX) models were generated using freshly resected patient tumors immediately transplanted into immunocompromised murine hosts without an...
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Bacterial Probes
Immunology Shirley (New York) October 30, 2024 1.00 Dollar US$FISH Probes were designed by sequencing the 16S rRNA for each bacterium, identifying hypervariable regions, and chemically synthesizing species-specific probes. These probes were specific when tested against a panel of nucleic acids from closely rela...
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COPD Models
Immunology Shirley (New York) October 30, 2024 1.00 Dollar US$Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. It is characterized by chronic airway inflammation, excessive mucus secretion, airway remodeling, and emphysema, leading to decreased lung function ...
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Human SCN8A Stable Cell Line
Immunology Shirley (New York) September 27, 2024 1.00 Dollar US$The human SCN8A gene encodes the pore-forming subunit of Nav1.6, a voltage-gated sodium channel expressed in central and peripheral nervous systems. Mutations in the mouse ortholog cause ataxia and other movement disorders. Nav1.6 channels are therap...
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Cav1.2
Immunology Shirley (New York) September 27, 2024 1.00 Dollar US$Cav1.2 plays an important role in the contraction of the heart. It is particularly important and well known for its expression in the heart where it mediates L-type currents, which causes calcium-induced calcium release from the ER Stores via ryanodi...
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Human TRPV3 Stable Cell Line
Immunology Shirley (New York) September 27, 2024 1.00 Dollar US$The TRPV3 channel belongs to the transient receptor potential channel (TRP) super-family that consists of 7 subfamilies. The channels exist as tetramers where each subunit consists of 6 putative trans-membrane domains. In this respect they have a sim...
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